Lung epithelial cells are increasingly recognized to be active effectors of microbial defense,
contributing to both innate and adaptive immune function in the lower respiratory tract. As …

Bronchopulmonary dysplasia (BPD) is the most common cause of morbidity and mortality in
preterm infants. A key histopathological feature of BPD is stunted late lung development …

Prosperous advances in understanding the cellular and molecular mechanisms of chronic
inflammation and airway remodeling in asthma have been made over the past several …

The inflammatory disorders collectively termed the seronegative spondyloarthropathies
(SpA) include ankylosing spondylitis (AS), psoriatic arthritis (PsA), reactive arthritis, the …

The respiratory tract is home to a diverse microbial community whose influence on local and
systemic immune responses is only beginning to be appreciated. Increasing reports have …

Respiratory diseases affect millions of people worldwide, and account for significant levels
of disability and mortality. The treatment of lung cancer and asthma with therapeutic …

Asthma is a prevalent, chronic inflammatory respiratory disease defined by airway
hyperresponsiveness (AHR), aberrant mucus production, and airway smooth muscle …

In obesity, disturbed glutamine metabolism contributes to enhanced inflammation by
inducing alterations in immune cells. As macrophages and innate lymphoid cells (ILCs) are …

Background: Aerobic training (AT) decreases airway inflammation in asthma, but the
underlying cellular and molecular mechanisms are not completely understood. Thus, this …

Since the airways are constantly exposed to various pathogens and foreign antigens,
various kinds of cells in the airways—including structural cells and immune cells—interact to …