Are animal models predictive for humans?

N Shanks, R Greek, J Greek - Philosophy, ethics, and humanities in …, 2009 - Springer
It is one of the central aims of the philosophy of science to elucidate the meanings of
scientific terms and also to think critically about their application. The focus of this essay is …

Morphological and molecular alterations in 1, 2 dimethylhydrazine and azoxymethane induced colon carcinogenesis in rats

M Perše, A Cerar - BioMed Research International, 2011 - Wiley Online Library
The dimethyhydrazine (DMH) or azoxymethane (AOM) model is a well‐established, well‐
appreciated, and widely used model of experimental colon carcinogenesis. It has many …

[图书][B] Hayes' principles and methods of toxicology

AW Hayes, T Kobets - 2023 - taylorfrancis.com
Hayes' Principles and Methods of Toxicology has long been established as a reliable and
informative reference for the concepts, methodologies, and assessments integral to …

Antioxidant, antimicrobial and toxicological properties of Schinus molle L. essential oils

M do Rosário Martins, S Arantes, F Candeias… - Journal of …, 2014 - Elsevier
Ethnopharmacological relevance Schinus molle L. has been used in folk medicine as
antibacterial, antiviral, topical antiseptic, antifungal, antioxidant, anti-inflammatory, anti …

[HTML][HTML] Systematic reviews of animal models: methodology versus epistemology

R Greek, A Menache - International journal of medical sciences, 2013 - ncbi.nlm.nih.gov
Systematic reviews are currently favored methods of evaluating research in order to reach
conclusions regarding medical practice. The need for such reviews is necessitated by the …

Health effects from long-range transported contaminants in Arctic top predators: an integrated review based on studies of polar bears and relevant model species

C Sonne - Environment international, 2010 - Elsevier
The aim of this review is to provide a thorough overview of the health effects from the
complexed biomagnified mixture of long-range transported industrial organochlorines …

[HTML][HTML] Refining animal models in fracture research: seeking consensus in optimising both animal welfare and scientific validity for appropriate biomedical use

JA Auer, A Goodship, S Arnoczky, S Pearce… - BMC musculoskeletal …, 2007 - Springer
In an attempt to establish some consensus on the proper use and design of experimental
animal models in musculoskeletal research, AOVET (the veterinary specialty group of the …

Counteract severe heat stress by including different forms of zinc in the rabbit bucks' diet

YM El-Gindy, SM Zahran, MH Ahmed, AM Ali… - Scientific Reports, 2023 - nature.com
The harmful influences of global warming on rabbit reproduction and industry attract global
attention. Zinc (Zn) is an important trace element with a wide list of functions in the male …

Toxicological and pharmacological properties of essential oils of Calamintha nepeta, Origanum virens and Thymus mastichina of Alentejo (Portugal)

SM Arantes, A Piçarra, M Guerreiro, C Salvador… - Food and Chemical …, 2019 - Elsevier
Three autochthonous flavouring herbs from Alentejo (Portugal), Calamintha nepeta (syn.
Clinopodium nepeta), Origanun virens and Thymus mastichina, were selected to evaluate …

Animal models for human diseases: an overview

J Hau - Sourcebook of models for biomedical research, 2008 - Springer
This chapter provides an introduction to the concept of laboratory animal models, focusing
on a general classification of animal models for the study of human diseases. Animal models …