Psychiatric disorders are debilitating diseases, affecting> 80 million people worldwide.
There are no causal cures for psychiatric disorders and available therapies only treat the …

This review outlined evidence that purinergic signaling is involved in the modulation of
blood-brain barrier (BBB) permeability. The functional and structural integrity of the BBB is …

Purpose Advances in functional imaging allowed us to visualize brain glucose metabolism
in vivo and non-invasively with [18F] fluoro-2-deoxyglucose (FDG) positron emission …

The zebrafish (Danio rerio) is an emergent model organism for assessing fear and anxiety-
like phenotypes. The short fin wild type (WT), and leopard (leo) are two zebrafish …

Resveratrol, a natural polyphenolic compound, has been studied as a neuroprotective
molecule. Our group has demonstrated that such effect is closely associated with modulation …

Plant pathogenic fungi seriously threaten agricultural production. There is an urgent need to
develop novel fungicides with low toxicity and high efficiency. In this study, we designed and …

Abstract Di-(2-ethylhexyl) phthalate (DEHP) is a widely used phthalate that possesses a
public health concern. Different concentrations of DEHP, including 50, 300, and 750 mg/kg …

The ketamine's potential for the treatment of refractory depression and anxiety has been
considered one the most important discoveries in the last years, however, repeated use of …

This study aimed to verify whether chronic exposure to nonylphenol (NP) induces anxiety
behavior in rats and explored NP's regulatory effect on the BDNF/TrkB/CREB signal network …

Major depressive disorder (MDD) leads to pervasive changes in the health of afflicted
patients. Despite advances in the understanding of MDD and its treatment, profound …