Parkinson's disease (PD) is the second most common progressive neurodegenerative
disease, affecting 1–2% of people over 65. The classic motor symptoms of PD result from …

Abstract Neuronal Calcium Sensor-1 (NCS-1) is a highly conserved calcium binding protein
which contributes to the maintenance of intracellular calcium homeostasis and regulation of …

A major hurdle for regeneration after spinal cord injury (SCI) is the ability of axons to
penetrate and grow through the scar tissue. After SCI, inflammatory cells, astrocytes and …

Brain injury that results in an initial behavioural deficit is frequently followed by spontaneous
recovery. The intrinsic mechanism of this functional recovery has never been fully …

Functional recovery following incomplete spinal cord injury (SCI) depends on the rewiring of
motor circuits during which supraspinal connections form new contacts onto spinal relay …

Chondroitin sulphate proteoglycans (CSPG s) are extracellular matrix molecules whose
inhibitory activity is attenuated by the enzyme chondroitinase ABC (C h ABC). Here we …

If and how neurons remodel their connections after CNS injury critically influences recovery
of function. Here, we investigate the role of the growth‐initiating transcription factor STAT3 …

Docosahexaenoic acid (DHA) is an ω-3 polyunsaturated fatty acid that is essential in brain
development and has structural and signaling roles. Acute DHA administration is …

Neural tissue engineering is premised on the integration of engineered living tissue with the
host nervous system to directly restore lost function or to augment regenerative capacity …

Prominent neuropathology following trauma, stroke, and various neurodegenerative
diseases includes neuronal degeneration as well as loss of long-distance axonal …