Omega-3 polyunsaturated fatty acids (ω-3 PUFAs) confer multiple health benefits and
decrease the risk of neurological disorders. Studies are needed, however, to identify …

A defection of blood circulation in the brain leads to ischemia, damage, and the death of
nerve cells. It is known that individual populations of GABAergic neurons are the least …

The long-term disabilities associated with spinal cord injury (SCI) are primarily due to the
absence of robust neuronal regeneration and functional plasticity. The inability of the axon to …

The remodeling of axonal circuits after injury requires the formation of new synaptic contacts
to enable functional recovery. Which molecular signals initiate such axonal and synaptic …

The calcium-binding protein frequenin (Frq), discovered in the fruit fly Drosophila, and its
mammalian homologue neuronal calcium sensor 1 (NCS-1) have been reported to affect …

Mammalian target of rapamycin (mTOR) functions as a master sensor of nutrients and
energy, and controls protein translation and cell growth. Deletion of phosphatase and tensin …

Neuronal calcium sensor-1 (NCS-1) protein is abundantly expressed in the central nervous
system and retinal neurons, where it regulates many vital processes such as synaptic …

Gene therapies hold great promise for the treatment of many neurodegenerative disorders
and traumatic injuries in the central nervous system. However, development of effective …

Object Unilateral contusions represent an increasingly popular model for studying the
pathways and recovery mechanisms of spinal cord injury (SCI). Current studies rely heavily …

During the past decades, new insights into mechanisms that limit plasticity and functional
recovery after spinal cord injury have spurred the development of novel approaches to …