Abstract Abiogenic metals Pb and Hg are highly toxic since chronic and/or acute exposure
often leads to severe neuropathologies. Mn2+ is an essential metal ion but in excess can …

Despite increasing knowledge on microRNAs, their role in the pathogenesis of neonatal
encephalopathy remains to be elucidated. Herein, we identify let-7b-5p as a significant …

The transcription factor forkhead box P2 (FOXP2) is believed to be important in the evolution
of human speech. A mutation in its DNA-binding domain causes severe speech impairment …

Abstract Neuronal calcium sensor 1 (NCS-1) is a high-affinity calcium-binding protein and its
ubiquitous expression in the nervous system implies a wide range of functions. To date, it …

Abstract Calcium (Ca2+) signaling is critical for neuronal functioning and requires the
concerted interplay of numerous Ca2+-binding proteins, including neuronal calcium sensor …

Neural tissue engineering offers tremendous promise to combat the effects of disease,
aging, or injury in the nervous system. Here we review neural tissue engineering with …

After an incomplete spinal cord injury (SCI), partial recovery of locomotion is accomplished
with time. Previous studies have established a functional link between extension of axon …

Inositol 1, 4, 5-trisphosphate receptors (InsP3Rs) are endoplasmic reticulum–localized
channels that mediate Ca 2+ release from the endoplasmic reticulum into the cytoplasm. We …

Spinal cord injury (SCI) is a severe condition leading to enduring motor deficits. When
lesions are incomplete, promoting spinal cord plasticity might be a useful strategy to elicit …

Traumatic brain injury (TBI) is an extremely complex disease and current systems classifying
TBI as mild, moderate, and severe often fail to capture this complexity. Neuroimaging cannot …