The use of an adeno-associated viral vector for efficient bicistronic expression of two genes in the central nervous system

TH Hutson, C Kathe, SC Menezes, MC Rooney… - Axon Growth and …, 2014 - Springer
Recombinant adeno-associated viral (AAV) vectors are one of the most promising
therapeutic delivery systems for gene therapy to the central nervous system (CNS) …

Characterising severe traumatic brain injury from fresh cerebral biopsy in living patients

PK Yip, S Hasan, CEG Uff - medRxiv, 2021 - medrxiv.org
Traumatic brain injury (TBI) is one of the most complex disorder in the most complex organ
in the body and current classifications of mild, moderate and severe often fail to capture this …

组织工程持久支架如何恢复神经系统结构和功能?

LA Struzyna, JP Harris, KS Katiyar, HI Chen… - 中国神经再生研究 …, 2015 - sjzsyj.com.cn
神经组织工程的前提是与主控神经系统工程化生物体组织的整合, 并直接使丧失功能恢复或增强
神经系统损伤或神经退行性疾病后的再生能力. 轴突通路断开, 即长距离纤维连接中枢神经系统 …

The Calcium-Binding Protein Frequenin Negatively Regulates Nociception

WLJ Yu - 2022 - search.proquest.com
Nociception is the sensory process that detects noxious stimuli, transduces signals, and
triggers response through various ion channels and synaptic mechanisms. The calcium …

[引用][C] 神经营养因子联合治疗促进脊髓轴索再生的研究现状

张水印, 顾兵, 李华南, 张国福 - 江西科技师范大学学报, 2014

[引用][C] 基因治疗脊髓损伤的研究进展

魏世坤, 赵红卫 - 中国脊柱脊髓杂志, 2013

[PDF][PDF] Novel mechanism of action for neuronal let-7b-5p in neonatal encephalopathy through the Hippo pathway

V Ponnusamy, R Ip, M Mohamed, P Clarke, E Wozniak… - 2021 - pdfs.semanticscholar.org
Despite increasing knowledge on microRNAs, their role in the pathogenesis of neonatal
encephalopathy remains to be elucidated. Herein, we identify let-7b-5p as a signi cant …

Identifying and characterizing functionally relevant microRNAs and 5'isomiRs in triple-negative breast cancer

J Jung - 2020 - archiv.ub.uni-heidelberg.de
Triple-negative breast cancer is a highly aggressive breast cancer subtype and the
treatment options are mainly limited to chemotherapy, however, the patients frequently …

Docosahexaenoic acid reduces microglia phagocytic activity via miR-124 and induces neuroprotection in rodent models of spinal cord contusion injury

MÁ Burguillos García, P Kei Yip, AL Bowes… - … Molecular Genetics, 28 …, 2019 - idus.us.es
Microglia are activated after spinal cord injury (SCI), but their phagocytic mechanisms and
link to neuroprotection remain incompletely characterized. Docosahexaenoic acid (DHA) …

[图书][B] Developing a neural implant to enable controlled alterations to brain architecture

NJ Weir - 2019 - search.proquest.com
Neuroscientific research frequently utilises loss of function experiments to attribute function
to a brain region. Gain of function experiments via cortical re-wiring would aid in validation of …