Recent advances on organelle specific Ru (II)/Ir (III)/Re (I) based complexes for photodynamic therapy
Organelle specificity is an important facet of more efficient and highly selective drugs with
reduced side effects which have now been the great challenge to the scientists. In …
reduced side effects which have now been the great challenge to the scientists. In …
Control and utilization of ruthenium and rhodium metal complex excited states for photoactivated cancer therapy
The use of visible light to produce highly selective and potent drugs through photodynamic
therapy (PDT) holds much potential in the treatment of cancer. PDT agents can be designed …
therapy (PDT) holds much potential in the treatment of cancer. PDT agents can be designed …
[PDF][PDF] An amphiphilic ruthenium polymetallodrug for combined photodynamic therapy and photochemotherapy in vivo
The success of several FDA-approved platinum anticancer drugs has stimulated increasing
interest in the development of new metallodrugs.[1] Ruthenium (Ru) complexes are potential …
interest in the development of new metallodrugs.[1] Ruthenium (Ru) complexes are potential …
Harnessing ruthenium (II) as photodynamic agents: Encouraging advances in cancer therapy
Despite their past triumphs, platinum-based therapeutics remain limited by chemo-
resistance and severe side effects. As an alternative therapeutic modality which bypasses …
resistance and severe side effects. As an alternative therapeutic modality which bypasses …
Luminescent ruthenium (II) polypyridine complexes for a wide variety of biomolecular and cellular applications
Ruthenium (II) polypyridine complexes are one of the most extensively studied and
developed systems in the family of luminescent transition-metal complexes. Notably, there …
developed systems in the family of luminescent transition-metal complexes. Notably, there …
Exploitation of Long-Lived 3IL Excited States for Metal–Organic Photodynamic Therapy: Verification in a Metastatic Melanoma Model
Members of a family of Ru (II)-appended pyrenylethynylene dyads were synthesized,
characterized according to their photophysical and photobiological properties, and …
characterized according to their photophysical and photobiological properties, and …
Ru (II) dyads derived from α-oligothiophenes: A new class of potent and versatile photosensitizers for PDT
G Shi, S Monro, R Hennigar, J Colpitts, J Fong… - Coordination Chemistry …, 2015 - Elsevier
Ru (II) dyads derived from organic units that impart low-lying 3 IL excited states combine the
most attractive features of organic photosensitizers with those of coordination complexes …
most attractive features of organic photosensitizers with those of coordination complexes …
A selective and cell-permeable mitochondrial calcium uniporter (MCU) inhibitor preserves mitochondrial bioenergetics after hypoxia/reoxygenation injury
JJ Woods, N Nemani, S Shanmughapriya… - ACS central …, 2019 - ACS Publications
Mitochondrial Ca2+ (mCa2+) uptake mediated by the mitochondrial calcium uniporter
(MCU) plays a critical role in signal transduction, bioenergetics, and cell death, and its …
(MCU) plays a critical role in signal transduction, bioenergetics, and cell death, and its …
New Ru(II) Complexes for Dual Photoreactivity: Ligand Exchange and 1O2 Generation
Conspectus Uncovering the factors that govern the electronic structure of Ru (II)–polypyridyl
complexes is critical in designing new compounds for desired photochemical reactions, and …
complexes is critical in designing new compounds for desired photochemical reactions, and …
Photoactivated in vitro anticancer activity of rhenium (I) tricarbonyl complexes bearing water-soluble phosphines
Fifteen water-soluble rhenium compounds of the general formula [Re (CO) 3 (NN)(PR3)]+,
where NN is a diimine ligand and PR3 is 1, 3, 5-triaza-7-phosphaadamantane (PTA), tris …
where NN is a diimine ligand and PR3 is 1, 3, 5-triaza-7-phosphaadamantane (PTA), tris …