A field guide to foldamers
The breadth of structure and function displayed by the molecules of biology is remarkable.
Considering that there are only three major biopolymer backbones (proteins, ribonucleic …
Considering that there are only three major biopolymer backbones (proteins, ribonucleic …
LNA (locked nucleic acids): synthesis and high-affinity nucleic acid recognition
A novel class of nucleic acid analogues, termed LNA (locked nucleic acids), is introduced.
Following the Watson–Crick base pairing rules, LNA forms duplexes with complementary …
Following the Watson–Crick base pairing rules, LNA forms duplexes with complementary …
Rational design of functional DNA with a non-ribose acyclic scaffold
The growing field of DNA technology requires new modified DNAs that can perform
advanced functions. No matter how we optimize the length and sequence of DNA using only …
advanced functions. No matter how we optimize the length and sequence of DNA using only …
A Novel Class of Oligonucleotide Analogues Containing 2'-O,3'-C-Linked [3.2.0]Bicycloarabinonucleoside Monomers: Synthesis, Thermal Affinity Studies, and …
NK Christensen, M Petersen, P Nielsen… - Journal of the …, 1998 - ACS Publications
Oligonucleotide analogues containing a novel 2 '-O, 3 '-C-linked [3.2. 0] bicyclonucleoside
have been efficiently synthesized. Enhanced thermal stabilities of duplexes toward both …
have been efficiently synthesized. Enhanced thermal stabilities of duplexes toward both …
Synthesis and evaluation of oligodeoxynucleotides containing acyclic nucleosides: introduction of three novel analogues and a summary
Novel flexible oligodeoxynucleotides containing (S)-1-(2, 3-dihydroxypropyl) thymine or 2′,
3′-seco-thymidine nucleoside analogues were synthesized on an automated DNA …
3′-seco-thymidine nucleoside analogues were synthesized on an automated DNA …
Enzymatic synthesis of DNA on glycerol nucleic acid templates without stable duplex formation between product and template
CH Tsai, J Chen, JW Szostak - Proceedings of the National …, 2007 - National Acad Sciences
Glycerol nucleic acid (GNA) is an interesting alternative base-pairing system based on an
acyclic, glycerol-phosphate backbone repeat unit. The question of whether DNA …
acyclic, glycerol-phosphate backbone repeat unit. The question of whether DNA …
Duplex formation of the simplified nucleic acid GNA
MK Schlegel, AE Peritz, K Kittigowittana… - …, 2007 - Wiley Online Library
Glycol nucleic acid (GNA) has an acyclic backbone of propylene glycol nucleosides that are
connected by phosphodiester bonds. This paper characterizes the duplex‐formation …
connected by phosphodiester bonds. This paper characterizes the duplex‐formation …
[HTML][HTML] Molecularly resolved, label-free nucleic acid sensing at solid–liquid interface using non-ionic DNA analogues
Nucleic acid-based biosensors, where the capture probe is a nucleic acid, eg, DNA or its
synthetic analogue xeno nucleic acid (XNA), offer interesting ways of eliciting clinically …
synthetic analogue xeno nucleic acid (XNA), offer interesting ways of eliciting clinically …
A novel class of conformationally restricted oligonucleotide analogues: synthesis of 2′, 3′-bridged monomers and RNA-selective hybridisation
A novel class of conformationally restricted oligonucleotide analogues: synthesis of 2A,3A-bridged
monomers and RNA-selective hy Page 1 O ButMe2SiO O O O O BnO O O OBn O BnO OBn HO …
monomers and RNA-selective hy Page 1 O ButMe2SiO O O O O BnO O O OBn O BnO OBn HO …
Oligodeoxynucleoside Phosphoramidates (P-NH 2 ): Synthesis and Thermal Stability of Duplexes With DNA and RNA Targets
S Peyrottes, JJ Vasseur, JL Imbach… - Nucleic acids …, 1996 - academic.oup.com
Syntheses of non ionic oligodeoxynucleoside phosphoramidates (P-NH 2) and mixed
phosphoramidate-phosphodiester oligomers were accomplished on automated solid …
phosphoramidate-phosphodiester oligomers were accomplished on automated solid …