[HTML][HTML] Fibro-fatty remodelling in arrhythmogenic cardiomyopathy

A Kohela, E van Rooij - Basic Research in Cardiology, 2022 - Springer
Arrhythmogenic cardiomyopathy (AC) is an inherited disorder characterized by lethal
arrhythmias and a risk to sudden cardiac death. A hallmark feature of AC is the progressive …

Growth factors: avenues for the treatment of myocardial infarction and potential delivery strategies

D Li, K Tian, J Guo, Q Wang, Z Qin, Y Lu… - Regenerative …, 2022 - Taylor & Francis
Acute myocardial infarction (AMI) is one of the leading causes of death worldwide. Despite
recent advances in clinical management, reoccurence of heart failure after AMI remains …

Combined methylglyoxal scavenger and collagen hydrogel therapy prevents adverse remodeling and improves cardiac function post‐myocardial infarction

CE Cimenci, NJR Blackburn… - Advanced Functional …, 2022 - Wiley Online Library
Methylglyoxal (MG) is a highly reactive dicarbonyl and the main precursor of advanced
glycation end‐products (AGEs). After myocardial infarction (MI), MG‐derived AGEs …

Intrapericardial Administration to Achieve Localized and Targeted Treatment for Cardiac Disease

Y Xu, Y Chen, JJ Tan, JP Ooi, Z Guo - Journal of Cardiovascular …, 2024 - Springer
Intrapericardial administration has been proposed as an alternative delivery route of
pharmacological agents via the bilaminar sac of pericardium surrounding the heart. To date …

[HTML][HTML] Development and in vitro characterization of polymeric nanoparticles containing recombinant adrenomedullin-2 intended for therapeutic angiogenesis

HC Quadros, LMF Santos, CS Meira, MI Khouri… - International Journal of …, 2020 - Elsevier
Cardiovascular diseases (CVD) are the leading cause of death worldwide. Growth factor
therapy has emerged as novel therapeutic strategy under investigation for CVD. In this …

Multiscale experimental and computational modeling approaches to characterize therapy delivery to the heart from an implantable epicardial biomaterial reservoir

RN Shirazi, S Islam, FM Weafer… - Advanced …, 2019 - Wiley Online Library
Delivery of therapeutic‐laden biomaterials to the epicardial surface of the heart presents a
promising method of treating a variety of diseased conditions by offering targeted, localized …

Pharmacokinetic advantage of ASD device promote drug absorption through the epicardium

R Mikrani, C Li, M Naveed, C Li, MMFA Baig… - Pharmaceutical …, 2020 - Springer
Purpose Due to low therapeutic efficacy and severe adverse reaction of systemic
administration for coronary heart disease (CHD) therapy, we designed a novel local target …

[PDF][PDF] 药物涂层球囊治疗冠状动脉原位病变后晚期管腔扩大现象的研究进展

杨新越, 郑悠扬, 林立 - 临床心, 2022 - en.whuhzzs.com
冠状动脉支架内再狭窄成为药物涂层球囊(DCB) 的主要适应证后, DCB 越来越多地作为其一线
治疗方式. 此外, 更多的临床证据支持DCB 在原位病变中的应用, 尤其是小血管病变 …

Drug delivery for cardiac regeneration

HM Eltaher, SS Said, LK El-Khordagui - Applications of Nanocomposite …, 2018 - Elsevier
Cardiovascular disease is one of the leading causes of death in the developed world.
Ischemic heart disease and acute myocardial infarction can cause progressive left …

Biomaterial Therapy Strategies for Treating the Infarcted Heart

C Eren Cimenci - 2022 - ruor.uottawa.ca
Ischemic cardiomyopathies, such as myocardial infarction (MI), are a leading cause of heart
failure in both men and women throughout the world. Despite timely intervention post-MI, the …