Mechanistic links between obesity, diabetes, and blood pressure: role of perivascular adipose tissue

SN Saxton, BJ Clark, SB Withers… - Physiological …, 2019 - journals.physiology.org
Obesity is increasingly prevalent and is associated with substantial cardiovascular risk.
Adipose tissue distribution and morphology play a key role in determining the degree of …

[HTML][HTML] Resveratrol, metabolic syndrome, and gut microbiota

A Chaplin, C Carpéné, J Mercader - Nutrients, 2018 - mdpi.com
Resveratrol is a polyphenol which has been shown to have beneficial effects on metabolic
syndrome-related alterations in experimental animals, including glucose and lipid …

[HTML][HTML] Preclinical and clinical evidence for the role of resveratrol in the treatment of cardiovascular diseases

BNM Zordoky, IM Robertson, JRB Dyck - Biochimica et Biophysica Acta …, 2015 - Elsevier
Cardiovascular disease is the leading cause of death worldwide. Despite advancements in
diagnosis and treatment of cardiovascular disease, the incidence of cardiovascular disease …

The effects of resveratrol on metabolic status in patients with type 2 diabetes mellitus and coronary heart disease

A Hoseini, G Namazi, A Farrokhian, Ž Reiner… - Food & function, 2019 - pubs.rsc.org
This study was performed to investigate the effects of resveratrol on metabolic status in
patients with type 2 diabetes mellitus (T2DM) and coronary heart disease (CHD). This …

Resveratrol confers endothelial protection via activation of the antioxidant transcription factor Nrf2

Z Ungvari, Z Bagi, A Feher… - American Journal …, 2010 - journals.physiology.org
Epidemiological studies suggest that Mediterranean diets rich in resveratrol are associated
with reduced risk of coronary artery disease. Resveratrol was also shown to confer …

Mitochondria and cardiovascular aging

DF Dai, PS Rabinovitch, Z Ungvari - Circulation research, 2012 - Am Heart Assoc
Old age is a major risk factor for cardiovascular diseases. Several lines of evidence in
experimental animal models have indicated the central role of mitochondria both in lifespan …

The role of oxidative stress in the pathophysiology of gestational diabetes mellitus

M Lappas, U Hiden, G Desoye, J Froehlich… - Antioxidants & redox …, 2011 - liebertpub.com
Normal human pregnancy is considered a state of enhanced oxidative stress. In pregnancy,
it plays important roles in embryo development, implantation, placental development and …

Nicotinamide mononucleotide (NMN) supplementation promotes neurovascular rejuvenation in aged mice: transcriptional footprint of SIRT1 activation, mitochondrial …

T Kiss, Á Nyúl-Tóth, P Balasubramanian, S Tarantini… - Geroscience, 2020 - Springer
Aging-induced structural and functional alterations of the neurovascular unit lead to
impairment of neurovascular coupling responses, dysregulation of cerebral blood flow, and …

Cardiovascular effects and molecular targets of resveratrol

H Li, N Xia, U Förstermann - Nitric oxide, 2012 - Elsevier
Resveratrol (3, 5, 4′-trihydroxy-trans-stilbene) is a polyphenol phytoalexin present in a
variety of plant species and has been implicated to explain the health benefits of red wine. A …

Resveratrol inhibits inflammation and ameliorates insulin resistant endothelial dysfunction via regulation of AMP‐activated protein kinase and sirtuin 1 activities: 白藜 …

Z Liu, C Jiang, J Zhang, B Liu, Q Du - Journal of Diabetes, 2016 - Wiley Online Library
摘要背景白藜芦醇是一种植物抗毒素, 对人体健康有益, 本研究的目的是调查白藜芦醇对胰岛素
信号和炎症中内皮功能障碍的影响. 方法: 使用棕榈酸酯激活内皮细胞, 以产生以胰岛素介导的一 …