Germ cells divide and differentiate in a unique local microenvironment under the control of
somatic cells. Signals released in this niche instruct oocyte reentry into the meiotic cell cycle …

Oocytes acquire developmental competence with progressive folliculogenesis. Cumulus
oocyte complexes (COCs) from small antral follicles have inherent low competence and are …

This study assessed the participation of amphiregulin (AREG) and bone morphogenetic
protein 15 (BMP15) during maturation of bovine cumulus-oocyte complexes (COCs) on …

STUDY HYPOTHESIS How does the ultrastructure of human oocytes matured in vitro
compare with oocytes collected from women after full hormonal stimulation? STUDY …

Estrogen is an important modulator of reproductive activity through nuclear receptors and G
protein–coupled estrogen receptor (GPER). Here, we observed that both estradiol and the …

Growth differentiation factor-9 (GDF9) and bone morphogenetic protein-15 (BMP15) are co-
expressed exclusively in oocytes throughout most of folliculogenesis and play central roles …

Context: Bone morphogenetic protein (BMP) 15 is an oocyte-specific growth factor, which,
together with growth differentiation factor (GDF) 9, regulates folliculogenesis and ovulation …

Recent studies have independently shown that cyclic adenosine 3′ 5′‐monophosphate
(cAMP) modulation prior to in vitro maturation (IVM) and epidermal growth factor (EGF)‐like …

Developmental competence of in vitro matured (IVM) oocytes needs to be improved and this
can potentially be achieved by adding recombinant bone morphogenetic protein 15 …

The administration of follicle-stimulating hormone (FSH) prior to oocyte retrieval improves
oocyte developmental competence. During bovine embryo production in vitro, however …