Activation of mouse cumulus-oocyte complex maturation in vitro through EGF-like activity of versican

KR Dunning, LN Watson, VJ Zhang… - Biology of …, 2015 - academic.oup.com
In vitro maturation of oocytes is suboptimal to in vivo maturation with altered gene
expression and compromised oocyte quality. The large proteoglycan versican is abundant in …

Significance of epidermal growth factor receptor signaling for acquisition of meiotic and developmental competence in mammalian oocytes

R Prochazka, M Blaha, L Němcová - Biology of Reproduction, 2017 - academic.oup.com
The surge in luteinizing hormone (LH) in preovulatory ovarian follicles triggers the
resumption of oocyte meiosis accompanied by expansion of surrounding cumulus cells and …

Coenzyme Q10 ameliorates the quality of mouse oocytes during in vitro culture

CH Lee, MK Kang, DH Sohn, HM Kim, J Yang, SJ Han - Zygote, 2022 - cambridge.org
Oxidative stress causes several diseases and dysfunctions in cells, including oocytes.
Clearly, oxidative stress influences oocyte quality during in vitro maturation and fertilization …

Combined epidermal growth factor and hyaluronic acid supplementation of in vitro maturation medium and its impact on bovine oocyte proteome and competence

GL Rios, J Buschiazzo, NC Mucci, GG Kaiser, A Cesari… - Theriogenology, 2015 - Elsevier
The conditions for in vitro oocyte maturation impact on cytoplasmic and nuclear processes in
the oocyte. These events are differentially influenced by the nature of the maturation inducer …

Simulated physiological oocyte maturation (SPOM) improves developmental competence of in vitro produced goat embryos

A Suresh, MK Shukla, D Kumar, OP Shrivastava… - Theriogenology, 2021 - Elsevier
The effect of simulated physiological oocyte maturation on the developmental competence,
reactive oxygen species production and apoptosis rate of in vitro produced goat embryos …

Nutrient pathways regulating the nuclear maturation of mammalian oocytes

SM Downs - Reproduction, Fertility and Development, 2015 - CSIRO Publishing
Oocyte maturation is defined as that phase of development whereby a fully grown oocyte
reinitiates meiotic maturation, completes one meiotic division with extrusion of a polar body …

[HTML][HTML] Interaction between epidermal growth factor receptor and CC motif chemokine receptor 2 in the ovulatory cascade

JG Conte, ML Tellechea, B Park… - Frontiers in Cell and …, 2023 - frontiersin.org
The epidermal growth factor receptor (EGFR) signaling pathway is one of the main pathways
responsible for propagating the luteinizing hormone (LH) signal throughout the cumulus …

Amphiregulin Supplementation During Pig Oocyte In Vitro Maturation Enhances Subsequent Development of Cloned Embryos by Promoting Cumulus Cell …

X Zhang, H Zhao, Y Li, Y Zhang, Y Liang… - Cellular …, 2022 - liebertpub.com
The oocyte in vitro maturation (IVM) technique is important in animal husbandry,
biomedicine, and human-assisted reproduction. However, the developmental potential of in …

Current perspectives on in vitro maturation and its effects on oocyte genetic and epigenetic profiles

C Lu, Y Zhang, X Zheng, X Song, R Yang, J Yan… - Science China Life …, 2018 - Springer
In vitro maturation (IVM), the maturation in culture of immature oocytes, has been used in
clinic for more than 20 years. Although IVM has the specific advantages of low cost and …

[HTML][HTML] NPR2 is involved in FSH-mediated mouse oocyte meiotic resumption

L Yang, Q Wei, W Li, Q Xi, X Zhao, B Ma - Journal of ovarian research, 2016 - Springer
Background Previous studies have reported that follicle-stimulating hormone (FSH) is often
added to culture media to induce oocyte meiotic resumption and maturation and to improve …