The gut microbiota is a complex and plastic consortium of microorganisms that are intricately
connected with human physiology. The liver is a central immunological organ that is …

Cholangiocarcinoma is the second most common primary liver cancer. Its incidence is low in
the Western world but is rising globally. Surgery, chemotherapy and radiation therapy have …

Abbreviations: AASLD, American Association for the Study of Liver Diseases; AIH,
autoimmune hepatitis; ALP, alkaline phosphatase; ASIR, age standardized incidence rate; …

Current sequencing-based analyses of faecal microbiota quantify microbial taxa and
metabolic pathways as fractions of the sample sequence library generated by each …

Primary sclerosing cholangitis (PSC) is a rare disorder characterised by multi-focal bile duct
strictures and progressive liver disease. Inflammatory bowel disease is usually present and …

Background and Aims Patients with inflammatory bowel disease (IBD) have an increased
risk of colorectal cancer (CRC). We performed a systematic review and meta-analysis to …

Gut dysbiosis is commonly observed in patients with cirrhosis and chronic gastrointestinal
disorders; however, its effect on antitumor immunity in the liver is largely unknown. Here we …

Research on the human microbiome has yielded numerous insights into health and disease,
but also has resulted in a wealth of experimental artifacts. Here, we present suggestions for …

Primary sclerosing cholangitis is a rare, chronic cholestatic liver disease characterised by
intrahepatic or extrahepatic stricturing, or both, with bile duct fibrosis. Inflammation and …

Primary sclerosing cholangitis (PSC) is characterized by progressive biliary inflammation
and fibrosis. Although gut commensals are associated with PSC, their causative roles and …