The gut-liver axis is widely implicated in the pathogenesis of liver diseases, where it is
increasingly the focus of clinical research. Recent studies trialling an array of therapeutic …

Objective The significance of the liver-microbiome axis has been increasingly recognised as
a major modulator of autoimmunity. The aim of this study was to take advantage of a large …

The gut microbiota has recently evolved as a new important player in the pathophysiology of
many intestinal and extraintestinal diseases. The liver is the organ which is in closest contact …

AIM To characterize the gut bacterial microbiota of patients with primary sclerosing
cholangitis (PSC) and ulcerative colitis (UC). METHODS Stool samples were collected and …

Primary sclerosing cholangitis (PSC) is a chronic cholestatic liver disease of unknown
aetiology for which there are no approved therapeutic options. Patients with PSC display …

Abstract gutMDisorder (http://bio-annotation. cn/gutMDisorder), a manually curated
database, aims at providing a comprehensive resource of dysbiosis of the gut microbiota in …

BACKGROUND: Primary sclerosing cholangitis (PSC) is a cholestatic liver disease with no
effective medical therapies. A perturbation of the gut microbiota has been described in …

Microbial cells significantly outnumber human cells in the body, and the microbial flora at
mucosal sites are shaped by environmental factors and, less intuitively, act on host immune …

Primary sclerosing cholangitis (PSC) offers unique opportunities to explore the gut–liver axis
owing to the close association between liver disease and colonic inflammation. It is well …

Recent work has highlighted the importance of confounder control in microbiome
association studies,. For instance, multiple pathologies previously linked to gut ecosystem …