[HTML][HTML] Antioxidant, anti-inflammatory and hepatoprotective activities of Terminalia bellirica and its bioactive component ellagic acid against diclofenac induced …

A Gupta, R Kumar, R Ganguly, AK Singh, HK Rana… - Toxicology reports, 2021 - Elsevier
Long term usage and overdose of diclofenac (DCF), an anti-inflammatory drug is known to
cause oxidative stress and liver injury. The present study reports the antioxidant, anti …

A role of connexin 43 on the drug-induced liver, kidney, and gastrointestinal tract toxicity with associated signaling pathways

R Katturajan, SE Prince - Life sciences, 2021 - Elsevier
Drug-induced organ toxicity/injury, especially in the liver, kidney, and gastrointestinal tract, is
a systematic disorder that causes oxidative stress formation and inflammation resulting in …

[PDF][PDF] Nigellalogy: a review on Nigella sativa

MT Islam, B Guha, S Hosen, TA Riaz… - MOJ Bioequiv …, 2017 - academia.edu
Nigella sativa and its constitutions including some isolated compounds are the potential
sources of remedies of varieties of ailments such as antioxidant, anti–inflammatory …

Structural Characterization, Antimicrobial Activity, and In Vitro Cytotoxicity Effect of Black Seed Oil

SJ Mohammed, HHH Amin, SB Aziz… - Evidence‐Based …, 2019 - Wiley Online Library
This study was aimed to investigate the structure of bioactive components of black seed oil
(BSO) and their antimicrobial and cytotoxic effects. Initially, the structural examination was …

[HTML][HTML] Phyllanthin prevents diethylnitrosamine (DEN) induced liver carcinogenesis in rats and induces apoptotic cell death in HepG2 cells

Y You, F Zhu, Z Li, LF Zhang, Y Xie… - Biomedicine & …, 2021 - Elsevier
Liver cancer is a critical clinical condition with augmented malignancy, rapid progression,
and poor prognosis. Liver cancer often initiates as fibrosis, develops as cirrhosis, and results …

Nigella sativa seeds mitigate the hepatic histo-architectural and ultrastructural changes induced by 4-nonylphenol in Clarias gariepinus

M Abd-Elkareem, AEDH Sayed, NSA Khalil… - Scientific Reports, 2023 - nature.com
Due to its prevalence in aquatic environments and potential cytotoxicity, 4-nonylphenol (4-
NP) has garnered considerable attention. As a medicinal plant with numerous biological …

An updated literature-based review: phytochemistry, pharmacology and therapeutic promises of Nigella sativa L.

MT Islam, MR Khan, SK Mishra - Oriental Pharmacy and Experimental …, 2019 - Springer
An in depth review on Nigella sativa and its derived constituents has been necessitated
which has been sketched in this paper from the research reports obtained from PubMed and …

Adverse effects induced by diclofenac, ibuprofen, and paracetamol toxicity on immunological and biochemical parameters in Swiss albino mice

S Gomaa - The journal of basic and applied zoology, 2018 - Springer
Background Nonsteroidal anti-inflammatory drugs (NSAIDs) are generally used to reduce
pain in different diseases acting as anti-inflammatory, antipyretic, and analgesic …

Caesalpinia bonducella Counteracts Paracetamol-Instigated Hepatic Toxicity via Modulating TNF-α and IL-6/10 Expression and Bcl-2 and Caspase-8/3 Signalling

S Nithiyanandam, SE Prince - Applied Biochemistry and Biotechnology, 2023 - Springer
Paracetamol is the most predominantly used antipyretic and analgesic drug. As paracetamol
is metabolised mostly in the liver, both deliberate and unintentional overdoses of …

Cardioprotective and Hepatoprotective Potential of Silymarin in Paracetamol-Induced Oxidative Stress

B Okiljević, N Martić, S Govedarica, B Andrejić Višnjić… - Pharmaceutics, 2024 - mdpi.com
Silymarin, derived from Silybum marianum, has been used in traditional medicine for various
ailments. In this study, the cardioprotective and hepatoprotective effects of silymarin against …