Interplay between diet, the gut microbiome, and atherosclerosis: Role of dysbiosis and microbial metabolites on inflammation and disordered lipid metabolism
L Anto, CN Blesso - The Journal of Nutritional Biochemistry, 2022 - Elsevier
Atherosclerosis remains the leading cause of death worldwide. Lifestyle modification,
including diet and exercise, is recommended to be the primary prevention strategy for …
including diet and exercise, is recommended to be the primary prevention strategy for …
Membrane lipids from gut microbiome-associated bacteria as structural and signalling molecules
Bacteria produce an array of diverse, dynamic and often complex lipid structures, some of
which function beyond their typical role in membrane structure. The model organism, E. coli …
which function beyond their typical role in membrane structure. The model organism, E. coli …
Lipidomic Analysis Reveals Differences in Bacteroides Species Driven Largely by Plasmalogens, Glycerophosphoinositols and Certain Sphingolipids
There has been increasing interest in bacterial lipids in recent years due, in part, to their
emerging role as molecular signalling molecules. Bacteroides thetaiotaomicron is an …
emerging role as molecular signalling molecules. Bacteroides thetaiotaomicron is an …
Lipidomic analysis of Porphyromonas gingivalis reveals novel glycerol bisphosphoceramide, phosphatidyl-, and phosphoglycerol dipeptide lipid families
Porphyromonas gingivalis, like other members of the phylum Bacteroidetes (synonym
Bacteroidota), synthesizes several classes of dihydroceramides and peptidolipids. Using a …
Bacteroidota), synthesizes several classes of dihydroceramides and peptidolipids. Using a …
Lipidome of the Bacteroides Genus Containing New Peptidolipid and Sphingolipid Families Revealed by Multiple-Stage Mass Spectrometry
CF Frankfater, MG Sartorio, E Valguarnera… - Biochemistry, 2023 - ACS Publications
The anaerobic bacteria of the Bacteroides fragilis group including Bacteroides
thetaiotaomicron, B. fragilis, Bacteroides vulgatus, and Bacteroides ovatus in genus …
thetaiotaomicron, B. fragilis, Bacteroides vulgatus, and Bacteroides ovatus in genus …
Structures and functions of the gut microbial lipidome
S Morozumi, M Ueda, N Okahashi, M Arita - Biochimica et Biophysica Acta …, 2022 - Elsevier
Microbial lipids provide signals that are responsible for maintaining host health and
controlling disease. The differences in the structures of microbial lipids have been shown to …
controlling disease. The differences in the structures of microbial lipids have been shown to …
Construction of a bacterial lipidomics analytical platform: Pilot validation with bovine paratuberculosis serum
PL Wood, E Erol - Metabolites, 2023 - mdpi.com
Lipidomics analyses of bacteria offer the potential to detect and monitor infections in a host
since many bacterial lipids are not present in mammals. To evaluate this omics approach …
since many bacterial lipids are not present in mammals. To evaluate this omics approach …
Spatially resolved lipidomics shows conditional transfer of lipids produced by Bacteroides thetaiotaomicron into the mouse gut
The extent to which bacterial lipids produced by the gut microbiota penetrate host tissues is
unclear. Here, we combined mass spectrometry approaches to identify lipids produced by …
unclear. Here, we combined mass spectrometry approaches to identify lipids produced by …
The multifaceted role of c-di-AMP signaling in the regulation of Porphyromonas gingivalis lipopolysaccharide structure and function
Background This study unveils the intricate functional association between cyclic di-3', 5'-
adenylic acid (c-di-AMP) signaling, cellular bioenergetics, and the regulation of …
adenylic acid (c-di-AMP) signaling, cellular bioenergetics, and the regulation of …
Metabolism of serine/glycine lipids by human gingival cells in culture
TM Guido, SD Ratcliffe, A Rahmlow… - Molecular Oral …, 2024 - Wiley Online Library
Porphyromonas gingivalis produces five classes of serine/glycine lipids that are recovered
in lipid extracts from periodontitis‐afflicted teeth and diseased gingival tissues, particularly at …
in lipid extracts from periodontitis‐afflicted teeth and diseased gingival tissues, particularly at …