Nicotine and other nicotinic agonists have been found to improve performance on attention
and memory tasks. Clinical studies using nicotine skin patches have demonstrated the …

Drug addiction is a brain disorder caused by the repetitive use of various chemicals which
alter normal functioning of the central nervous system with consequent behavioral …

Several lines of evidence suggest that nicotine may be useful in treating the symptoms of
Attention-Deficit/Hyperactivity Disorder (ADHD). The current study was an acute, placebo …

Nicotinic acetylcholine receptors have been found to be important for maintaining optimal
performance on a variety of cognitive tasks. In humans, nicotine-induced improvement of …

The pedunculopontine tegmental nucleus (PPTg) contains a population of cholinergic
neurons (the Ch5 group) and non-cholinergic neurons. There appears to be functional …

Postsynaptic responses of dopamine (DA) neurons in the substantia nigra pars compacta
(SNc) to stimulation of the pedunculopontine tegmental nuclei (PPN) were studied in in vitro …

The properties of the binding sites for radiolabeled acetylcholine (measured in the presence
of atropine), nicotine, and alpha-bungarotoxin were compared in brain tissue prepared from …

In order to determine whether the cholinergic fibres that innervate the substantia nigra make
synaptic contact with dopaminergic neurons of the substantia nigra pars compacta, a double …

Neuronal nicotinic acetylcholine receptors (nAChRs) represent a large family of ligand-
gated cation channels with diverse structures and properties. In contrast to the muscular …

The habenula (Hb) is an evolutionary well-conserved structure located in the epithalamus.
The Hb receives inputs from the septum, basal ganglia, hypothalamus, anterior cingulate …