The conduct of molecular and laboratory animal circadian rhythm research has increased
exponentially in the past few decades, such that today investigations are being performed by …

Atherosclerosis, a chronic inflammatory disease of the arteries that appears to have been as
prevalent in ancient as in modern civilizations, is predisposing to life-threatening and life …

The pharmacodynamics of hypertension medications can be significantly affected by
circadian rhythms in the biological mechanisms of the 24 h blood pressure (BP) pattern …

The journal Chronobiology International was launched in 1984 by co-Editors-in-Chief Alain
Reinberg and Michael Smolensky as a visionary step forward for the emerging science of …

Several prospective studies consistently report elevated asleep blood pressure (BP) and
blunted sleep-time relative systolic BP (SBP) decline (non-dipping) are jointly the most …

Introduction Clinical hypertension trials typically rely on homeostatic principles, including
single time-of-day office blood pressure (BP) measurements (OBPM), rather than circadian …

The origin of biological rhythms goes back to the very beginning of life. They are observed in
the animal and plant world at all levels of organization, from cells to ecosystems. As early as …

New scientific evidence raises awareness concerning the human-specific interplay among
primary environmental conditions, such as the light–dark cycle, activity–rest alternation …

Although it has been understood for several decades that the actions of drugs can vary
markedly depending on the time of day of exposure, consideration of daily timing is too often …

Cardiac circadian rhythms are an important regulator of body functions, including cardiac
activities and blood pressure. Disturbance of circadian rhythm is known to trigger and …