Clinical applications of plasma proteomics and peptidomics: Towards precision medicine

B He, Z Huang, C Huang… - PROTEOMICS–Clinical …, 2022 - Wiley Online Library
In the context of precision medicine, disease treatment requires individualized strategies
based on the underlying molecular characteristics to overcome therapeutic challenges …

Recent advances in aptamer-based nanosystems and microfluidics devices for the detection of ovarian cancer biomarkers

S Vandghanooni, Z Sanaat, J Barar, K Adibkia… - TrAC Trends in …, 2021 - Elsevier
Cost-efficient sensitive detection of solid tumor markers in patients' serums with high
accuracy and specificity has been a striking challenge. The early detection of ovarian cancer …

Aptamer-modified magnetic SERS substrate for label-based determination of cardiac troponin I

C Lin, L Li, J Feng, Y Zhang, X Lin, H Guo, R Li - Microchimica Acta, 2022 - Springer
A sensitive label-based SERS strategy composed of magnetic bimetallic nanoparticles Fe 3
O 4@ Ag@ Au, specific aptamer, and Bradford method was developed for the quantitative …

Mass spectrometry-based proteomic technology and its application to study skeletal muscle cell biology

P Dowling, D Swandulla, K Ohlendieck - Cells, 2023 - mdpi.com
Voluntary striated muscles are characterized by a highly complex and dynamic proteome
that efficiently adapts to changed physiological demands or alters considerably during …

[HTML][HTML] Application of multiple omics to understand postoperative delirium pathophysiology in humans

SM Vasunilashorn, ST Dillon, ER Marcantonio… - Gerontology, 2023 - karger.com
Delirium, an acute change in cognition, is common, morbid, and costly, particularly among
hospitalized older adults. Despite growing knowledge of its epidemiology, far less is known …

Recent progress in the development of aptasensors for cancer diagnosis: focusing on aptamers against cancer biomarkers

S Vandghanooni, Z Sanaat, R Farahzadi… - Microchemical …, 2021 - Elsevier
The early diagnosis of cancer is a very critical step in the treatment and management of the
disease. However, some cancers might manifest with nonspecific symptoms resulting in the …

SELEX against whole-cell bacteria resulted in lipopolysaccharide binding aptamers

D Yılmaz, T Muslu, A Parlar, H Kurt, M Yüce - Journal of Biotechnology, 2022 - Elsevier
Nucleic acid aptamers are target-specific oligonucleotides selected from combinatorial
libraries through an iterative in vitro screening process known as Systemic Evolution of …

[HTML][HTML] Regulation of transforming growth factor-β signaling as a therapeutic approach to treating colorectal cancer

J Maslankova, I Vecurkovska… - World Journal of …, 2022 - ncbi.nlm.nih.gov
According to data from 2020, Slovakia has long been among the top five countries with the
highest incidence rate of colorectal cancer (CRC) worldwide, and the rate is continuing to …

Current methods for identifying plasma membrane proteins as cancer biomarkers

E Jong, A Kocer - Membranes, 2023 - mdpi.com
Plasma membrane proteins are a special class of biomolecules present on the cellular
membrane. They provide the transport of ions, small molecules, and water in response to …

Future perspectives on aptamer for application in food authentication

N Mohamad, NI Azizan, NFK Mokhtar, S Mustafa… - Analytical …, 2022 - Elsevier
Food fraudulence and food contamination are major concerns, particularly among
consumers with specific dietary, cultural, lifestyle, and religious requirements. Current food …