Predicting outcomes in radiation oncology—multifactorial decision support systems

P Lambin, RGPM Van Stiphout… - Nature reviews Clinical …, 2013 - nature.com
With the emergence of individualized medicine and the increasing amount and complexity of
available medical data, a growing need exists for the development of clinical decision …

In vivo dosimetry in external beam radiotherapy

B Mijnheer, S Beddar, J Izewska, C Reft - Medical physics, 2013 - Wiley Online Library
In vivo dosimetry (IVD) is in use in external beam radiotherapy (EBRT) to detect major errors,
to assess clinically relevant differences between planned and delivered dose, to record …

Dosimetry tools and techniques for IMRT

DA Low, JM Moran, JF Dempsey, L Dong… - Medical …, 2011 - Wiley Online Library
Intensity modulated radiation therapy (IMRT) poses a number of challenges for properly
measuring commissioning data and quality assurance (QA) radiation dose distributions. This …

Decision support systems for personalized and participative radiation oncology

P Lambin, J Zindler, BGL Vanneste… - Advanced drug delivery …, 2017 - Elsevier
A paradigm shift from current population based medicine to personalized and participative
medicine is underway. This transition is being supported by the development of clinical …

Validation of a method for in vivo 3D dose reconstruction for IMRT and VMAT treatments using on‐treatment EPID images and a model‐based forward‐calculation …

E Van Uytven, T Van Beek, PM McCowan… - Medical …, 2015 - Wiley Online Library
Purpose: Radiation treatments are trending toward delivering higher doses per fraction
under stereotactic radiosurgery and hypofractionated treatment regimens. There is a need …

Online 3D EPID‐based dose verification: proof of concept

H Spreeuw, R Rozendaal, I Olaciregui‐Ruiz… - Medical …, 2016 - Wiley Online Library
Purpose: Delivery errors during radiotherapy may lead to medical harm and reduced life
expectancy for patients. Such serious incidents can be avoided by performing dose …

The ESTRO Breur Lecture 2009. From population to voxel-based radiotherapy: exploiting intra-tumour and intra-organ heterogeneity for advanced treatment of non …

P Lambin, SF Petit, HJWL Aerts, WJC van Elmpt… - Radiotherapy and …, 2010 - Elsevier
Evidence is accumulating that radiotherapy of non-small cell lung cancer patients can be
optimized by escalating the tumour dose until the normal tissue tolerances are met. To …

First online real‐time evaluation of motion‐induced 4D dose errors during radiotherapy delivery

T Ravkilde, S Skouboe, R Hansen, E Worm… - Medical …, 2018 - Wiley Online Library
Purpose In radiotherapy, dose deficits caused by tumor motion often far outweigh the
discrepancies typically allowed in plan‐specific quality assurance (QA). Yet, tumor motion is …

An in vivo dose verification method for SBRT–VMAT delivery using the EPID

PM McCowan, E Van Uytven, T Van Beek… - Medical …, 2015 - Wiley Online Library
Purpose: Radiation treatments have become increasingly more complex with the
development of volumetric modulated arc therapy (VMAT) and the use of stereotactic body …

First clinical results of adaptive radiotherapy based on 3D portal dosimetry for lung cancer patients with atelectasis treated with volumetric-modulated arc therapy …

LCGG Persoon, AGTM Egelmeer, MC Öllers… - Acta …, 2013 - Taylor & Francis
Atelectasis in lung cancer patients can change rapidly during a treatment course, which may
displace the tumor/healthy tissues, or change tissue densities locally. This may result in …