Polysaccharide utilization loci: fueling microbial communities

JM Grondin, K Tamura, G Déjean, DW Abbott… - Journal of …, 2017 - Am Soc Microbiol
The complex carbohydrates of terrestrial and marine biomass represent a rich nutrient
source for free-living and mutualistic microbes alike. The enzymatic saccharification of these …

[HTML][HTML] Fungal cellulases

CM Payne, BC Knott, HB Mayes, H Hansson… - Chemical …, 2015 - ACS Publications
Lignocellulosic biomass has enormous potential to contribute to worldwide energy,
chemical, and material demands in a renewable, sustainable manner. In the United States …

dbCAN3: automated carbohydrate-active enzyme and substrate annotation

J Zheng, Q Ge, Y Yan, X Zhang, L Huang… - Nucleic Acids …, 2023 - academic.oup.com
Carbohydrate active enzymes (CAZymes) are made by various organisms for complex
carbohydrate metabolism. Genome mining of CAZymes has become a routine data analysis …

Diet-induced extinctions in the gut microbiota compound over generations

ED Sonnenburg, SA Smits, M Tikhonov… - Nature, 2016 - nature.com
The gut is home to trillions of microorganisms that have fundamental roles in many aspects
of human biology, including immune function and metabolism,. The reduced diversity of the …

Bacteroidetes use thousands of enzyme combinations to break down glycans

P Lapébie, V Lombard, E Drula, N Terrapon… - Nature …, 2019 - nature.com
Unlike proteins, glycan chains are not directly encoded by DNA, but by the specificity of the
enzymes that assemble them. Theoretical calculations have proposed an astronomical …

The carbohydrate-active enzymes database (CAZy) in 2013

V Lombard, H Golaconda Ramulu, E Drula… - Nucleic acids …, 2014 - academic.oup.com
Abstract The Carbohydrate-Active Enzymes database (CAZy; http://www. cazy. org) provides
online and continuously updated access to a sequence-based family classification linking …

Expansion of the enzymatic repertoire of the CAZy database to integrate auxiliary redox enzymes

A Levasseur, E Drula, V Lombard, PM Coutinho… - Biotechnology for …, 2013 - Springer
Background Since its inception, the carbohydrate-active enzymes database (CAZy;
http://www. cazy. org) has described the families of enzymes that cleave or build complex …

Glycan complexity dictates microbial resource allocation in the large intestine

A Rogowski, JA Briggs, JC Mortimer, T Tryfona… - Nature …, 2015 - nature.com
The structure of the human gut microbiota is controlled primarily through the degradation of
complex dietary carbohydrates, but the extent to which carbohydrate breakdown products …

Erratum to: comparative analysis of fungal genomes reveals different plant cell wall degrading capacity in fungi

Z Zhao, H Liu, C Wang, JR Xu - BMC genomics, 2014 - Springer
The version of this article published in BMC Genomics 2013, 14: 274, contains 9
unpublished genomes (Botryobasidium botryosum, Gymnopus luxurians, Hypholoma …

A discrete genetic locus confers xyloglucan metabolism in select human gut Bacteroidetes

J Larsbrink, TE Rogers, GR Hemsworth, LS McKee… - Nature, 2014 - nature.com
A well-balanced human diet includes a significant intake of non-starch polysaccharides,
collectively termed 'dietary fibre', from the cell walls of diverse fruits and vegetables. Owing …