High-impact RCTs without prospective informed consent: a systematic review

R Dhamanaskar, JF Merz - Journal of Investigative Medicine, 2020 - journals.sagepub.com
The prevalence of randomized controlled trials (RCTs) performed without fully informed
prospective consent from subjects is unknown. We performed this study to estimate the …

Rising Intensive Care Costs in Bronchiolitis Infants—Is Nasal High Flow the Culprit?

D Franklin, A Schibler - Pediatric Critical Care Medicine, 2022 - journals.lww.com
Bronchiolitis remains the most common reason for nonelective hospital and intensive care
admissions among young children (1). In an attempt to reduce the burden of the disease …

Acute bronchiolitis in Switzerland–Current management and comparison over the last two decades

K Hartog, C Ardura‐Garcia, J Hammer… - Pediatric …, 2022 - Wiley Online Library
Background Although international guidelines and Cochrane reviews emphasize that
therapies do not alter the natural course of acute viral bronchiolitis (AVB), they are still …

Factors associated with treatment failure of high-flow nasal cannula among children with bronchiolitis: a single-centre retrospective study

M D'Alessandro, T Vanniyasingam… - Paediatrics & Child …, 2021 - academic.oup.com
Objectives Bronchiolitis is the most common viral lower respiratory tract infection in children
under age 2 for which high-flow nasal cannula (HFNC) is increasingly used. Understanding …

[HTML][HTML] Factors influencing health professionals' use of high-flow nasal cannula therapy for infants with bronchiolitis–A qualitative study

SL O'Brien, L Haskell, EJ Tavender, S Wilson… - Frontiers in …, 2023 - frontiersin.org
Aim: To explore the factors influencing the use of high-flow nasal cannula (HFNC) therapy
for infants with bronchiolitis. Design: Qualitative approach using semi-structured interviews …

Assessment of peak inspiratory flow in young infants with acute viral bronchiolitis: physiological basis for initial flow setting in patients supported with high-flow nasal …

C Milési, A Requirand, A Douillard, J Baleine… - The Journal of …, 2021 - Elsevier
Objective To assess the inspiratory demand in young infants with acute viral bronchiolitis to
provide a physiological basis for initial flow setting for patients supported with high flow …

A pilot study of heated and humidified low flow oxygen therapy: an assessment in infants with mild and moderate bronchiolitis (HHOT AIR study)

DY Chen, ED Zee, G Gildengorin… - Pediatric …, 2019 - Wiley Online Library
Background Heated and humidified high flow nasal cannula oxygen therapy has been used
in children with severe bronchiolitis. No data exists in children with mild to moderate …

[HTML][HTML] SpO2/FiO2 as a predictor of high flow nasal cannula outcomes in children with acute hypoxemic respiratory failure

GE Kim, SH Choi, M Park, JH Jung, M Lee, SY Kim… - Scientific Reports, 2021 - nature.com
The high-flow nasal cannula (HFNC) is a useful treatment modality for acute hypoxemic
respiratory failure (AHRF) in children. We compared the ability of the oxygen saturation to …

Transition to Weight-Based High-Flow Nasal Cannula Use Outside of the ICU for Bronchiolitis

RJ Willer, PW Brady, AN Tyler, JD Treasure… - JAMA Network …, 2024 - jamanetwork.com
Importance Most children's hospitals have adopted weight-based high-flow nasal cannula
(HFNC) bronchiolitis protocols for use outside of the intensive care unit (ICU) setting …

[HTML][HTML] Changes in Ventilation Practices for Bronchiolitis in the Hospital Ward and Need for ICU Transfer over the Last Decade

R Solana-Gracia, V Modesto i Alapont… - Journal of Clinical …, 2022 - mdpi.com
There is limited evidence of the potential benefits of the use of high-flow nasal cannula
(HFNC) for the management of bronchiolitis in the ward. Our aim is to describe the …