Abstract l-ascorbic acid (L-AA, vitamin C) is an essential vitamin that is widely used as a
nutrient or medicine in the pharmaceuticals, cosmetics, food, beverage and feed additive …

This review discusses the physical and chemical properties of nicotinamide redox cofactor
dependent glucose dehydrogenase (NAD (P) dependent GDH) and its extensive application …

Heme-dependent oxygenases (ie P450 monooxygenases and peroxygenases) are highly
selective catalysts for the selective oxyfunctionalisation or organic compounds. Both enzyme …

Controlled halogenation of chemically versatile substrates is difficult to achieve. Here we
describe a unique flavin-dependent halogenase, PltM, which is capable of utilizing a wide …

Cofactor imbalance obstructs the productivities of metabolically engineered cells. Herein, we
employed a minimally perturbing system, xylose reductase and lactose (XR/lactose), to …

During the optimization of processes in biocatalysis, the limitations of mass transfer and
enzyme stability have to be overcome. To achieve these goals, aeration with microbubbles …

Switching cofactor preference of oxidoreductases from NADPH to NADH by rational
engineering, replacing the expensive cofactor NADP+ with the cheap cofactor NAD+, is a …

The successful realization of a sustainable manufacturing bioprocess and the maximization
of its production potential and capacity are the main concerns of a bioprocess engineer. A …

Glucose dehydrogenase (GDH) is a NAD (P)+ dependent oxidoreductase, which is useful in
glucose determination kits, glucose biosensors, cofactor regeneration, and biofuel cells …

Abstract Background Genetic modifications in Bacillus subtilis have allowed the conversion
of myo-inositol into scyllo-inositol, which is proposed as a therapeutic agent for Alzheimer's …