Measurement of cell proliferation by labeling of DNA with stable isotope-labeled glucose: Studies in vitro, in animals, and in humans
DC Macallan, CA Fullerton, RA Neese… - Proceedings of the …, 1998 - National Acad Sciences
A method for measuring DNA synthesis and, thus, cell proliferation, in vivo is presented. The
technique consists of administering [6, 6-2H2] Glc or [U-13C] Glc, isolating genomic DNA …
technique consists of administering [6, 6-2H2] Glc or [U-13C] Glc, isolating genomic DNA …
[HTML][HTML] Methylenetetrahydrofolate reductase 677C→ T polymorphism and folate status affect one-carbon incorporation into human DNA deoxynucleosides
EP Quinlivan, SR Davis, KP Shelnutt… - The Journal of …, 2005 - Elsevier
The methylenetetrahydrofolate reductase (MTHFR) 677C→ T polymorphism is thought to
influence the partitioning of 1-carbon units between methylation and other components of 1 …
influence the partitioning of 1-carbon units between methylation and other components of 1 …
Mechanism of α-tocopheryl succinate-induced apoptosis of promyelocytic leukemia cells
S Yamamoto, H Tamai, R Ishisaka, T Kanno… - Free radical …, 2000 - Taylor & Francis
Selective induction of apoptosis in tumor cells is important for treating patients with cancer.
Because oxidative stress plays an important role in the process of apoptosis, we studied the …
Because oxidative stress plays an important role in the process of apoptosis, we studied the …
Measuring DNA Synthesis Rates with [1-13C]Glycine
P Chen, FP Abramson - Analytical chemistry, 1998 - ACS Publications
We have devised and evaluated a stable-isotopic method for measuring DNA synthesis
rates. The probe is [1-13C] glycine that is incorporated into purines via de novo biosynthesis …
rates. The probe is [1-13C] glycine that is incorporated into purines via de novo biosynthesis …
Dünndarmveränderungen unter Zytostatika
R Ecknauer - Dünndarm B, 1983 - Springer
Zusammenfassung Limitierende Faktoren der Krebschemotherapie sind die
Nebenwirkungen auf rasch proliferierende Zellsysteme wie die Hämopoese (M arsh 1976) …
Nebenwirkungen auf rasch proliferierende Zellsysteme wie die Hämopoese (M arsh 1976) …
5-Iodo-2′-Deoxyuridine
WH Prusoff, MS Chen, PH Fischer, TS Lin… - Mechanism of Action of …, 1979 - Springer
Iodinated pyrimidines were first synthesized by Johnson and Johns (1905–1906), and a
systematic study of the biologic activities of various purine and pyrimidine base analogs was …
systematic study of the biologic activities of various purine and pyrimidine base analogs was …
The synthesis of alanine multilabeled with stable isotopes
SD Dimitrijevich, MD Scanlon… - Journal of Labelled …, 1982 - Wiley Online Library
The synthesis of alanine multilabeled with stable isotopes Page 1 Journal of Labelled
Compounds and Radiophamaceuticals - Vol. IX, No. 5 73 THE SYNTHESIS OF ALANINE …
Compounds and Radiophamaceuticals - Vol. IX, No. 5 73 THE SYNTHESIS OF ALANINE …
Mass spectrometry in cancer research
J Roboz - Advances in Cancer Research, 1978 - Elsevier
Publisher Summary A mass spectrometric analysis provides both unequivocal identification
and quantification of the constituents of interest, often in the presence of a host of similarly …
and quantification of the constituents of interest, often in the presence of a host of similarly …
The Measurement of Cell Turnover Rates Using Stable Isotope‐Labelled Thymidine: Experiments On the Small Intestine and On A Transplantable Lymphatic Tumour …
HA Heck, RL Dyer, M Anbar, FA Becker - Cell Proliferation, 1978 - Wiley Online Library
Multilabelled, non‐radioactive thymidine and tritiated thymidine were incorporated
simultaneously into the DNA of a rapidly‐growing, transplantable mouse lymphoma and the …
simultaneously into the DNA of a rapidly‐growing, transplantable mouse lymphoma and the …