Antimalarial drug efficacy in uncomplicated malaria should be assessed parasitologically in
large, community-based trials, enrolling the age groups most affected by clinical disease …

The intensification of malaria control interventions has resulted in its global decline, but it
remains a significant public health burden especially in sub-Saharan Africa (sSA) …

Plasmodium falciparum isolates were obtained from Thai patients attending a malaria clinic
on the Thai-Kampuchean border over 4 cross-sectional surveys carried out at 3-monthly …

On the western border of Thailand, Plasmodium falciparum has become resistant to almost
all antimalarial agents. The molecular basis of resistance in these parasite populations has …

Background Single nucleotide polymorphism (SNP) genotyping provides the means to
develop a practical, rapid, inexpensive assay that will uniquely identify any Plasmodium …

Plasmodium falciparum is the major cause of malaria morbidity and mortality in the world.
Biologic and antigenic diversity is a characteristic of this parasite and infections can consist …

Description of the genetic structure of malaria parasite populations is central to an
understanding of the spread of multiple-locus drug and vaccine resistance. The Plasmodium …

In the past, assessment of drug efficacy against Plasmodium falciparum malaria has been
performed by microscopy, screening for parasites in blood smears. However, in areas of …

As many malaria-endemic countries move towards elimination of Plasmodium falciparum,
the most virulent human malaria parasite, effective tools for monitoring malaria epidemiology …

Genotyping frequently is used to distinguish recrudescent from new infections in antimalarial
drug efficacy trials, but methodology and interpretation of results have not been …