Inflammatory and infectious upper respiratory diseases associate with 41 genomic loci and type 2 inflammation

EC Saarentaus, J Karjalainen, JT Rämö… - Nature …, 2023 - nature.com
Inflammatory and infectious upper respiratory diseases (ICD-10: J30-J39), such as diseases
of the sinonasal tract, pharynx and larynx, are growing health problems yet their genomic …

Energetic mitochondrial failing in vitiligo and possible rescue by cardiolipin

ML Dell'Anna, M Ottaviani, D Kovacs, S Mirabilii… - Scientific Reports, 2017 - nature.com
Vitiligo is characterized by death or functional defects of epidermal melanocytes through still
controversial pathogenic process. Previously, we showed that mitochondria-driven pre …

Circulating vitamin D levels and risk of vitiligo: Evidence from meta-analysis and two-sample mendelian randomization

J Song, K Liu, W Chen, B Liu, H Yang, L Lv… - Frontiers in …, 2021 - frontiersin.org
Background: The association between circulating vitamin D levels and risk of vitiligo was
inconsistent among observational studies, and whether these observed associations were …

Rare copy number variation in autoimmune Addison's disease

H Artaza, D Eriksson, K Lavrichenko… - Frontiers in …, 2024 - frontiersin.org
Autoimmune Addison's disease (AAD) is a rare but life-threatening endocrine disorder
caused by an autoimmune destruction of the adrenal cortex. A previous genome-wide …

Current landscape of oculocutaneous albinism in Japan

K Okamura, T Suzuki - Pigment Cell & Melanoma Research, 2021 - Wiley Online Library
Oculocutaneous albinism (OCA), which is roughly divided into non‐syndromic and
syndromic OCA, is a group of autosomal recessive disorders caused by mutations in genes …

Antimelanocyte antibodies: a possible role in patients with vitiligo

MA El-Gayyar, ME Helmy, ER Amer… - Indian Journal of …, 2020 - journals.lww.com
Background: Vitiligo is an acquired depigmenting skin disorder with multifactorial
pathogenesis including genetic, autoimmune, and neuronal factors. Both humoral-and cell …

Redundancy analysis, genome‐wide association studies and the pigmentation of brown trout (Salmo trutta L.)

T Valette, M Leitwein, JM Lascaux… - Journal of Fish …, 2023 - Wiley Online Library
The association of molecular variants with phenotypic variation is a main issue in biology,
often tackled with genome‐wide association studies (GWAS). GWAS are challenging, with …

TMT-based quantitative proteomic and physiological analyses on serums of Chinese patients with active vitiligo

Z Chen, Y Li, S Nie, Z Wu - Clinical, Cosmetic and Investigational …, 2023 - Taylor & Francis
Purpose Vitiligo is an acquired depigmented skin disorder. Though genetic background,
autoimmune dysregulation, and oxidative stress were reported involved in the development …

tauFisher predicts circadian time from a single sample of bulk and single-cell pseudobulk transcriptomic data

J Duan, MN Ngo, SS Karri, LC Tsoi… - Nature …, 2024 - nature.com
As the circadian clock regulates fundamental biological processes, disrupted clocks are
often observed in patients and diseased tissues. Determining the circadian time of the …

Network pharmacological mechanisms of Vernonia anthelmintica (L.) in the treatment of vitiligo: Isorhamnetin induction of melanogenesis via up-regulation of …

JY Wang, H Chen, YY Wang, XQ Wang, HY Chen… - BMC Systems …, 2017 - Springer
Background Vitiligo is a long-term skin disease characterized by the loss of pigment in the
skin. The current therapeutic approaches are limited. Although the anti-vitiligo mechanisms …