Exploring the extracellular matrix in health and disease using proteomics
IN Taha, A Naba - Essays in biochemistry, 2019 - portlandpress.com
The extracellular matrix (ECM) is a complex assembly of hundreds of proteins that
constitutes the scaffold of multicellular organisms. In addition to providing architectural and …
constitutes the scaffold of multicellular organisms. In addition to providing architectural and …
[HTML][HTML] Identification of key biomarkers and immune infiltration in the synovial tissue of osteoarthritis by bioinformatics analysis
W Cai, H Li, Y Zhang, G Han - PeerJ, 2020 - peerj.com
Background Osteoarthritis (OA) is the most common chronic degenerative joint disease and
is mainly characterized by cartilage degeneration, subcartilage bone hyperplasia …
is mainly characterized by cartilage degeneration, subcartilage bone hyperplasia …
[HTML][HTML] Identification and verification of ferroptosis-related genes in the synovial tissue of osteoarthritis using bioinformatics analysis
L Xia, N Gong - Frontiers in Molecular Biosciences, 2022 - frontiersin.org
Background: Osteoarthritis (OA) is a major factor causing pain and disability. Studies
performed to date have suggested that synovitis is possibly a critical OA-related pathological …
performed to date have suggested that synovitis is possibly a critical OA-related pathological …
Blocking HOTAIR protects human chondrocytes against IL-1β-induced cell apoptosis, ECM degradation, inflammatory response and oxidative stress via regulating …
J Wang, X Luo, S Cai, J Sun, S Wang, X Wei - International …, 2021 - Elsevier
Background Long non-coding RNA (lncRNA) HOX transcript antisense RNA (HOTAIR)
contributes to cartilage damages including osteoarthritis (OA). While, its role and mechanism …
contributes to cartilage damages including osteoarthritis (OA). While, its role and mechanism …
Arsenic induces human chondrocyte senescence and accelerates rat articular cartilage aging
YP Chung, YW Chen, TI Weng, RS Yang, SH Liu - Archives of toxicology, 2020 - Springer
Arsenic-contaminated drinking water is known to be a serious human health problem. A
previous epidemiological study has indicated that arsenic levels in blood were higher in …
previous epidemiological study has indicated that arsenic levels in blood were higher in …
[HTML][HTML] Recent advances in enzyme-related biomaterials for arthritis treatment
XH Liu, JY Ding, ZH Zhu, XC Wu, YJ Song… - Frontiers in …, 2022 - frontiersin.org
Arthritis is a group of highly prevalent joint disorders, and osteoarthritis (OA) and rheumatoid
arthritis are the two most common types. The high prevalence of arthritis causes severe …
arthritis are the two most common types. The high prevalence of arthritis causes severe …
Proteomic analysis reveals commonly secreted proteins of mesenchymal stem cells derived from bone marrow, adipose tissue, and synovial membrane to show …
Y Lee, YS Park, NY Choi, YI Kim… - Stem Cells …, 2021 - Wiley Online Library
Paracrine factors secreted by mesenchymal stem cells (MSCs) reportedly modulate
inflammation and reparative processes in damaged tissues and have been explored for …
inflammation and reparative processes in damaged tissues and have been explored for …
[HTML][HTML] Circ_0116061 regulated the proliferation, apoptosis, and inflammation of osteoarthritis chondrocytes through regulating the miR-200b-3p/SMURF2 axis
W Zheng, G Hou, Y Li - Journal of Orthopaedic Surgery and Research, 2021 - Springer
Abstract Background Circular RNA (circRNA) has been shown to be associated with
osteoarthritis (OA) progression. Circ_0116061 has been found to be highly expressed in OA …
osteoarthritis (OA) progression. Circ_0116061 has been found to be highly expressed in OA …
[HTML][HTML] Integration of Transcriptome and MicroRNA Profile Analysis of iMSCs Defines Their Rejuvenated State and Conveys Them into a Novel Resource for Cell …
V Konteles, I Papathanasiou, M Tzetis, E Goussetis… - Cells, 2023 - mdpi.com
Although MSCs grant pronounced potential for cell therapies, several factors, such as their
heterogeneity restrict their use. To overcome these limitations, iMSCs (MSCs derived from …
heterogeneity restrict their use. To overcome these limitations, iMSCs (MSCs derived from …
[HTML][HTML] Knockdown of Circ_0037658 alleviates IL-1β-induced osteoarthritis progression by serving as a sponge of miR-665 to regulate ADAMTS5
N Li, Y Wang, X Wu - Frontiers in Genetics, 2022 - frontiersin.org
Background: Osteoarthritis (OA) is a chronic musculoskeletal degeneration disease which
brings great pain to patients and a tremendous burden on the world's medical resources …
brings great pain to patients and a tremendous burden on the world's medical resources …