Enrichments of post‐translational modifications in proteomic studies

L Pieroni, F Iavarone, A Olianas… - Journal of separation …, 2020 - Wiley Online Library
More than 300 different protein post‐translational modifications are currently known, but only
a few have been extensively investigated because modified proteoforms are commonly …

[HTML][HTML] Glycation and a spark of ALEs (advanced lipoxidation end products)–igniting RAGE/Diaphanous-1 and cardiometabolic disease

L Arivazhagan, R López-Díez, A Shekhtman… - Frontiers in …, 2022 - frontiersin.org
Obesity and non-alcoholic fatty liver disease (NAFLD) are on the rise world-wide; despite
fervent advocacy for healthier diets and enhanced physical activity, these disorders persist …

[HTML][HTML] Soluble receptor for advanced glycation end-products regulates age-associated cardiac fibrosis

F Scavello, F Zeni, G Milano, F Macrì… - … Journal of Biological …, 2021 - ncbi.nlm.nih.gov
Myocardial aging increases the cardiovascular risk in the elderly. The Receptor for
Advanced Glycation End-products (RAGE) is involved in age-related disorders. The soluble …

[HTML][HTML] Advanced lipoxidation end products (ALEs) as RAGE binders: Mass spectrometric and computational studies to explain the reasons why

M Mol, G Degani, C Coppa, G Baron, L Popolo… - Redox biology, 2019 - Elsevier
Abstract Advanced Lipoxidation End-products (ALEs) are modified proteins that can act as
pathogenic factors in several chronic diseases. Several molecular mechanisms have so far …

Maillard proteomics: Opening new pages

A Soboleva, R Schmidt, M Vikhnina, T Grishina… - International Journal of …, 2017 - mdpi.com
Protein glycation is a ubiquitous non-enzymatic post-translational modification, formed by
reaction of protein amino and guanidino groups with carbonyl compounds, presumably …

Glycation reaction and the role of the receptor for advanced glycation end-products in immunity and social behavior

N Leerach, A Harashima, S Munesue, K Kimura… - Glycoconjugate …, 2021 - Springer
The receptor for advanced glycation end-products (receptor for AGEs, RAGE) is a pattern
recognition receptor. The interaction of RAGE with its ligands, such as AGEs, S100 proteins …

New insights into the efficiency of thymol synergistic effect with p-cymene in inhibiting advanced glycation end products: A multi-way analysis based on spectroscopic …

S Abbasi, S Gharaghani, A Benvidi… - … of Pharmaceutical and …, 2018 - Elsevier
Protein glycation in the body is one of the main reasons of diabetes complications. The
electrochemical studies on the inhibitory mechanism of glycation are rather scarce. Thus, it …

Electrochemistry of Alzheimer disease amyloid beta peptides

AM Chiorcea-Paquim, TA Enache… - Current Medicinal …, 2018 - ingentaconnect.com
Alzheimer's disease (AD) is a widespread form of dementia that is estimated to affect 44.4
million people worldwide. AD pathology is closely related to the accumulation of amyloid …

Unveiling the molecular mechanisms underpinning biorecognition of early-glycated human serum albumin and receptor for advanced glycation end products

A Tramarin, M Naldi, G Degani, L Lupu… - Analytical and …, 2020 - Springer
Serum levels of early-glycated albumin are significantly increased in patients with diabetes
mellitus and may play a role in worsening inflammatory status and sustaining diabetes …

Amoxicillin Haptenation of α-Enolase is Modulated by Active Site Occupancy and Acetylation

JM González-Morena, FJ Sánchez-Gómez… - Frontiers in …, 2022 - frontiersin.org
Allergic reactions to antibiotics are a major concern in the clinic. ß-lactam antibiotics are the
class most frequently reported to cause hypersensitivity reactions. One of the mechanisms …