Direct Cell Radiolabeling for in Vivo Cell Tracking with PET and SPECT Imaging

PJ Gawne, F Man, PJ Blower… - Chemical reviews, 2022 - ACS Publications
The arrival of cell-based therapies is a revolution in medicine. However, its safe clinical
application in a rational manner depends on reliable, clinically applicable methods for …

Iron homeostasis in health and disease

R Gozzelino, P Arosio - International journal of molecular sciences, 2016 - mdpi.com
Iron is required for the survival of most organisms, including bacteria, plants, and humans. Its
homeostasis in mammals must be fine-tuned to avoid iron deficiency with a reduced oxygen …

[HTML][HTML] Iron mediated toxicity and programmed cell death: A review and a re-examination of existing paradigms

R Eid, NTT Arab, MT Greenwood - … et Biophysica Acta (BBA)-Molecular Cell …, 2017 - Elsevier
Iron is an essential micronutrient that is problematic for biological systems since it is toxic as
it generates free radicals by interconverting between ferrous (Fe 2+) and ferric (Fe 3+) forms …

The role of Fe, Zn, and Cu in pregnancy

K Grzeszczak, S Kwiatkowski, D Kosik-Bogacka - Biomolecules, 2020 - mdpi.com
Iron (Fe), copper (Cu), and zinc (Zn) are microelements essential for the proper functioning
of living organisms. These elements participatein many processes, including cellular …

[HTML][HTML] circSnx12 is involved in ferroptosis during heart failure by targeting miR-224-5p

H Zheng, L Shi, C Tong, Y Liu, M Hou - Frontiers in Cardiovascular …, 2021 - frontiersin.org
Circular RNA (circRNA) is a subclass of non-coding RNAs that enables the circular
transcripts resistant to the exonuclease digestion. Iron homeostasis is essential for the body …

The Iron age of host–microbe interactions

MP Soares, G Weiss - EMBO reports, 2015 - embopress.org
Microbes exert a major impact on human health and disease by either promoting or
disrupting homeostasis, in the latter instance leading to the development of infectious …

The effects of iron overload on mitochondrial function, mitochondrial dynamics, and ferroptosis in cardiomyocytes

N Sumneang, N Siri-Angkul, S Kumfu… - Archives of Biochemistry …, 2020 - Elsevier
Excessive iron accumulation in the heart can lead to iron overload cardiomyopathy (IOC),
the leading cause of death in hemochromatosis patients. Current understanding regarding …

Nano-liposomes of lycopene reduces ischemic brain damage in rodents by regulating iron metabolism

Y Zhao, Z Xin, N Li, S Chang, Y Chen, L Geng… - Free Radical Biology …, 2018 - Elsevier
In order to discover new drug delivery approaches and to understand the mechanism of iron
overload in cerebral ischemia/reperfusion (I/R), we aimed to investigate the effects of …

Iron metabolism and related genetic diseases: A cleared land, keeping mysteries

P Brissot, O Loréal - Journal of hepatology, 2016 - Elsevier
Body iron has a very close relationship with the liver. Physiologically, the liver synthesizes
transferrin, in charge of blood iron transport; ceruloplasmin, acting through its ferroxidase …

Innate nutritional immunity

G Núñez, K Sakamoto, MP Soares - The Journal of Immunology, 2018 - journals.aai.org
Iron (Fe) is an essential micronutrient for both microbes and their hosts. The biologic
importance of Fe derives from its inherent ability to act as a universal redox catalyst, co …