[HTML][HTML] The innate and T-cell mediated immune response during acute and chronic gammaherpesvirus infection

V Rex, R Zargari, M Stempel, S Halle… - Frontiers in Cellular …, 2023 - frontiersin.org
Immediately after entry into host cells, viruses are sensed by the innate immune system,
leading to the activation of innate antiviral effector mechanisms including the type I interferon …

[HTML][HTML] Kaposi's sarcoma-associated herpesvirus, the etiological agent of all epidemiological forms of Kaposi's sarcoma

A Jary, M Veyri, A Gothland, V Leducq, V Calvez… - Cancers, 2021 - mdpi.com
Simple Summary Kaposi's sarcoma-associated herpesvirus (KSHV) is one of the seven
oncogenic viruses currently recognized by the International Agency for Research on Cancer …

[PDF][PDF] KSHV episome tethering sites on host chromosomes and regulation of latency-lytic switch by CHD4

A Kumar, Y Lyu, Y Yanagihashi, C Chantarasrivong… - Cell reports, 2022 - cell.com
Kaposi sarcoma-associated herpesvirus (KSHV) establishes a latent infection in the cell
nucleus, but where KSHV episomal genomes are tethered and the mechanisms underlying …

[HTML][HTML] NAT10-dependent N4‐acetylcytidine modification mediates PAN RNA stability, KSHV reactivation, and IFI16-related inflammasome activation

Q Yan, J Zhou, Z Wang, X Ding, X Ma, W Li… - Nature …, 2023 - nature.com
Abstract N-acetyltransferase 10 (NAT10) is an N 4‐acetylcytidine (ac4C) writer that catalyzes
RNA acetylation at cytidine N4 position on tRNAs, rRNAs and mRNAs. Recently, NAT10 and …

Shiftless restricts viral gene expression and influences RNA granule formation during Kaposi's sarcoma-associated herpesvirus lytic replication

W Rodriguez, T Mehrmann, D Hatfield… - Journal of …, 2022 - Am Soc Microbiol
Herpesviral infection reflects thousands of years of coevolution and the constant struggle
between virus and host for control of cellular gene expression. During Kaposi's sarcoma …

[HTML][HTML] Bcl-xL is required to protect endothelial cells latently infected with KSHV from virus induced intrinsic apoptosis

LN Moore, DL Holmes, A Sharma… - PLoS …, 2023 - journals.plos.org
Kaposi's Sarcoma herpesvirus (KSHV) is the etiologic agent of Kaposi's Sarcoma (KS), a
highly vascularized tumor common in AIDS patients and many countries in Africa. KSHV is …

CRISPR/Cas9 gene editing: A new therapeutic approach in the treatment of infection and autoimmunity

I Mohammadzadeh, D Qujeq, T Yousefi, GA Ferns… - IUBMB …, 2020 - Wiley Online Library
CRISPR/Cas9 (clustered regularly interspaced short palindromic repeats/CRISPR‐
associated protein9) may be viewed as an adaptive bacterial immune system. When a virus …

[HTML][HTML] Molecular Mechanisms of Flavonoids against Tumor Gamma-Herpesviruses and Their Correlated Cancers—A Focus on EBV and KSHV Life Cycles and …

STS Hassan, M Šudomová - International Journal of Molecular Sciences, 2022 - mdpi.com
Epstein–Barr virus (EBV) and Kaposi sarcoma-associated herpesvirus (KSHV) are cancer-
causing viruses that belong to human gamma-herpesviruses. They are DNA viruses known …

[HTML][HTML] Single-cell analysis of Kaposi's sarcoma-associated herpesvirus infection in three-dimensional air-liquid interface culture model

KL Jung, UY Choi, A Park, SS Foo, S Kim… - PLoS …, 2022 - journals.plos.org
The oral cavity is the major site for transmission of Kaposi's sarcoma-associated herpesvirus
(KSHV), but how KSHV establishes infection and replication in the oral epithelia remains …

[HTML][HTML] Human gammaherpesvirus 8 oncogenes associated with Kaposi's sarcoma

AO Lopes, PN Marinho, LAS Medeiros… - International Journal of …, 2022 - mdpi.com
Kaposi's sarcoma-associated herpesvirus (KSHV), also known as human
gammaherpesvirus 8 (HHV-8), contains oncogenes and proteins that modulate various …