Intra-host tumor virus variants may influence the pathogenesis and treatment responses of
some virally-associated cancers. However, the intra-host variability of Kaposi sarcoma …

Emerging evidence has identified viral circular RNAs (circRNAs) in human cells infected by
viruses, interfering with the immune system and inducing diseases including human cancer …

Reprogrammed metabolism is regarded as a hallmark of cancer and offers a selective
advantage to tumor cells during carcinogenesis. The redox equilibrium is necessary for …

Simple Summary Epigenetic reprogramming of the KSHV genome plays a central role in
lytic replication of Kaposi's sarcoma-associated herpesvirus (KSHV). Hypoxia, a common …

Herpesviruses are extremely successful parasites that have evolved over millions of years to
develop a variety of mechanisms to coexist with their hosts and to maintain host-to-host …

Since the identification of the first human oncogenic virus in 1964, viruses have been
studied for their potential role in aiding the development of cancer. Through the modulation …

Appreciation of the properties of arsenic trioxide (ATO) has redefined the treatment
landscape for acute promyelocytic leukaemia (APL) and offers promise as a treatment for …

Basic leucine zipper (bZIP) transcription factors (TFs) govern diverse cellular processes and
cell fate decisions. The hallmark of the leucine zipper domain is the heptad repeat, with …

Kaposi's sarcoma-associated herpesvirus (KSHV) ORF57 is an RNA-binding
posttranscriptional regulator. We recently applied an affinity-purified anti-ORF57 antibody to …

About 15% of all human cancers have a viral etiology. Although progress has been made,
understanding the viral oncogenesis and associated molecular mechanisms remain …