Amphetamine-related drugs neurotoxicity in humans and in experimental animals: Main mechanisms

R Moratalla, A Khairnar, N Simola, N Granado… - Progress in …, 2017 - Elsevier
Amphetamine-related drugs, such as 3, 4-methylenedioxymethamphetamine (MDMA) and
methamphetamine (METH), are popular recreational psychostimulants. Several preclinical …

Mechanisms of the psychostimulant effects of caffeine: implications for substance use disorders

S Ferré - Psychopharmacology, 2016 - Springer
Background The psychostimulant properties of caffeine are reviewed and compared with
those of prototypical psychostimulants able to cause substance use disorders (SUD) …

[HTML][HTML] The role of adenosine receptors in psychostimulant addiction

I Ballesteros-Yáñez, CA Castillo, S Merighi… - Frontiers in …, 2018 - frontiersin.org
Adenosine receptors (AR) are a family of G-protein coupled receptors, comprised of four
members, named A 1, A 2A, A 2B, and A 3 receptors, found widely distributed in almost all …

Neuroprotective and therapeutic effect of caffeine on the rat model of Parkinson's disease induced by rotenone

YA Khadrawy, AM Salem, KA El-Shamy… - Journal of Dietary …, 2017 - Taylor & Francis
The present study aimed to investigate the protective and therapeutic effects of caffeine on
rotenone-induced rat model of Parkinson's disease (PD). Rats were divided into control, PD …

The effect of CYP1A2 genotype on the ergogenic properties of caffeine during resistance exercise: a randomized, double-blind, placebo-controlled, crossover study

R Rahimi - Irish Journal of Medical Science (1971-), 2019 - Springer
Aim The purpose of this study was to examine the effect of CYP1A2-163C> A polymorphism
on the ergogenic effects of caffeine supplementation during a resistance exercise (RE) …

[HTML][HTML] Caffeine augments the instruction of anti-inflammatory macrophages by the conditioned medium of mesenchymal stem cells

N Shushtari, SMA Froushani - Cell Journal (Yakhteh), 2017 - ncbi.nlm.nih.gov
Objective Mesenchymal stem cells (MSCs) have been shown to produce adenosine,
express adenosine receptors, and communicate with macrophages and other cells …

Caffeine protects dopaminergic neurons from dopamine-induced neurodegeneration via synergistic adenosine-dopamine D2-like receptor interactions in transgenic …

RVM Manalo, PMB Medina - Frontiers in neuroscience, 2018 - frontiersin.org
Previous studies have suggested that caffeine reduces the risk of L-DOPA-induced
dyskinesia. However, caffeine is also known to promote dopamine signaling, which …

Neurochemical and neurotoxic effects of MDMA (ecstasy) and caffeine after chronic combined administration in mice

AM Górska, K Kamińska, A Wawrzczak-Bargieła… - Neurotoxicity …, 2018 - Springer
Abstract MDMA (3, 4-methylenedioxymethamphetamine) is a psychostimulant popular as a
recreational drug because of its effect on mood and social interactions. MDMA acts at …

MDMA alone affects sensorimotor and prepulse inhibition responses in mice and rats: tips in the debate on potential MDMA unsafety in human activity

M Marti, M Neri, S Bilel, M Di Paolo, R La Russa… - Forensic …, 2019 - Springer
Purpose MDMA is a psychoactive drug that has been increasingly abused worldwide, due to
its entactogenic properties. However, concerns on its safety exist, particularly regarding its …

[HTML][HTML] Bebidas cafeínadas energizantes: efectos neurológicos y cardiovasculares

CI Manrique, CL Arroyave-Hoyos, D Galvis-Pareja - Iatreia, 2018 - scielo.org.co
Las bebidas cafeínadas energizantes están compuestas esencialmente de cafeína, hidratos
de carbono y suplementos dietarios. Aunque los fabricantes defienden que estas bebidas …