Sudden cardiac death (SCD) is the leading cause of mortality in athletes during sport. A
variety of mostly hereditary, structural, or electrical cardiac disorders are associated with …

Congenital long QT syndrome (LQTS) encompasses a group of heritable conditions that are
associated with cardiac repolarization dysfunction. Since its initial description in 1957, our …

Sudden cardiac death (SCD) is the leading cause of mortality in athletes during sport. A
variety of mostly hereditary, structural or electrical cardiac disorders are associated with …

1From Mayo Clinic, Rochester, Minnesota; 2Fondazione Salvatore Maugeri University of
Pavia, Pavia, Italy and New York University, New York, New York; 3University Hospital …

Endophenotypes, measurable components unseen by the unaided eye along the pathway
between disease and distal genotype, have emerged as an important concept in the study of …

Background—The prevalence of genetic arrhythmogenic diseases is unknown. For the long-
QT syndrome (LQTS), figures ranging from 1: 20 000 to 1: 5000 were published, but none …

To identify genes involved in cardiac arrhythmia, we investigated patients with long OT
syndrome (LOT), an inherited disorder causing sudden death from a ventricular …

Objective.—To develop clinical, demographic, and pathological profiles of young
competitive athletes who died suddenly. Design.—Systematic evaluation of clinical …

Long QT syndrome (LQT) is an inherited disorder that causes sudden death from cardiac
arrhythmias, specifically torsade de pointes and ventricular fibrillation. We previously …

Background Primary ventricular tachyarrhythmias are rarely seen in children. Among them,
catecholaminergic polymorphic ventricular tachycardia has a poor spontaneous outcome. Its …