Auxin and its transport play a role in plant tolerance to arsenite‐induced oxidative stress in Arabidopsis thaliana

A Krishnamurthy… - Plant, cell & environment, 2013 - Wiley Online Library
The role of auxin in plant development is well known; however, its possible function in root
response to abiotic stress is poorly understood. In this study, we demonstrate a novel role of …

A polysaccharide of Dendrobium officinale ameliorates H2O2-induced apoptosis in H9c2 cardiomyocytes via PI3K/AKT and MAPK pathways

J Zhang, Y Guo, J Si, X Sun, G Sun, J Liu - International Journal of …, 2017 - Elsevier
Dendrobium officinale is one valuable traditional Chinese medicine, which has skyscraping
medicinal value. Polysaccharide is the main active ingredient in D. officinale; its antioxidant …

Ginsenoside Rg1 inhibits apoptosis by increasing autophagy via the AMPK/mTOR signaling in serum deprivation macrophages

P Yang, L Ling, W Sun, J Yang, L Zhang… - Acta biochimica et …, 2018 - academic.oup.com
Abstract Ginsenoside Rg1 (Rg1) has been widely used in a broad range of cardiovascular
and cerebral–vascular diseases because of its unique therapeutic properties. However, the …

[HTML][HTML] Ginsenoside Rg1 inhibits microglia pyroptosis induced by lipopolysaccharide through regulating STAT3 signaling

Y Yao, C Li, F Qian, Y Zhao, X Shi, D Hong… - Journal of …, 2021 - ncbi.nlm.nih.gov
Purpose Neuroinflammation runs through the whole process of nervous system diseases
and brain injury. Inflammasomes are thought to be especially relevant to immune …

Cardioprotective effect of salvianolic acid B against arsenic trioxide-induced injury in cardiac H9c2 cells via the PI3K/Akt signal pathway

M Wang, G Sun, X Sun, H Wang, X Meng, M Qin, J Sun… - Toxicology letters, 2013 - Elsevier
The clinical use of arsenic trioxide (ATO), a potent anti-neoplastic agent, is often limited
because of its severe cardiotoxicity. Salviae miltiorrhiza is widely used for the treatment of …

[HTML][HTML] Arsenic induces polyadenylation of canonical histone mRNA by down-regulating stem-loop-binding protein gene expression

J Brocato, L Fang, Y Chervona, D Chen, K Kiok… - Journal of Biological …, 2014 - ASBMB
The replication-dependent histone genes are the only metazoan genes whose messenger
RNA (mRNA) does not terminate with a poly (A) tail at the 3′-end. Instead, the histone …

[HTML][HTML] Protective effects of Myrica rubra flavonoids against hypoxia/reoxygenation-induced cardiomyocyte injury via the regulation of the PI3K/Akt/GSK3β pathway

M Wang, Y Liu, RL Pan, RY Wang… - International …, 2019 - spandidos-publications.com
Myrica rubra is well known for its delicious taste and high nutritional value. The present
study investigated the potential protective effects and mechanisms of M. rubra flavonoids …

[HTML][HTML] Cell cycle arrest and apoptotic cell death in cultured human gastric carcinoma cells mediated by arsenic trioxide

QS Shao, ZY Ye, ZQ Ling, JJ Ke - World Journal of …, 2005 - ncbi.nlm.nih.gov
AIM: To investigate the effect of arsenic trioxide on human gastric cancer cell line MKN45
with respect to both cytotoxicity and induction of apoptosis in vitro. METHODS: MKN45 cells …

Hydrogen peroxide induces the activation of the phospholipase C-γ1 survival pathway in PC12 cells: protective role in apoptosis

W Yuan, J Guo, X Li, Z Zou, G Chen, J Sun… - Acta Biochim …, 2009 - academic.oup.com
It has been reported that phospholipase C-γ1 (PLC-γ1) plays an important protective role in
hydrogen peroxide (H2O2)-induced pheochromocytoma (PC) 12 cells death. However, most …

流式细胞术研究细胞凋亡的方法与技术

潘春留, 闫雷, 卿素珠, 关伟军, 马月辉 - 现代生物医学进展, 2009 - cqvip.com
细胞发生凋亡时, 会伴随着一系列形态学, 生物化学及分子生物学性质的变化, 包括细胞皱缩,
核染色质凝聚, 细胞膜通透性改变, Caspases 激活, 线粒体跨膜电位降低, 膜磷酯酰丝氨酸外化 …