Plant-derived natural products for drug discovery: current approaches and prospects

N Nasim, IS Sandeep, S Mohanty - The Nucleus, 2022 - Springer
Nature has abundant source of drugs that need to be identified/purified for use as essential
biologics, either individually or in combination in the modern medical field. These drugs are …

Relationship between the therapeutic potential of various plant-derived bioactive compounds and their related microRNAs in neurological disorders

X Dong, J Nao - Phytomedicine, 2023 - Elsevier
Background Neurological disorders, such as ischemic stroke, spinal cord injury,
neurodegenerative diseases, and glioblastoma often lead to long-term disability and death …

Preparation of Nitrogen and Sulfur Co-Doped Fluorescent Carbon Dots from Cellulose Nanocrystals as a Sensor for the Detection of Rutin

T Zhang, Q Ji, J Song, H Li, X Wang, H Shi, M Niu… - Molecules, 2022 - mdpi.com
The poor water solubility, large particle size, and low accessibility of cellulose, the most
abundant bioresource, have restricted its generalization to carbon dots (CDs). Herein …

Optimization of sample extraction and injection-related parameters in HILIC performance for polar metabolite analysis. Application to the study of a model of …

M Morán-Garrido, P Muñoz-Escudero… - … of Chromatography A, 2022 - Elsevier
HILIC is a separation technique increasingly used for the study of polar metabolites.
However, HILIC suffers of a drawback related to the solvents used for these analyses …

Advances and strategies for capillary electrophoresis in the characterization of traditional Chinese medicine: A review of the past decade (2011–2021)

SA Shamsi, J Patel - Frontiers in Analytical Science, 2023 - frontiersin.org
While traditional Chinese medicine (TCM) is considered a valuable resource for drug
discovery and form a potential basis for drug development, they also carry substantial safety …

[HTML][HTML] Online preconcentration and determination of anthraquinones in Cassiae Semen tea by salting-out assisted liquid‒liquid extraction coupled with dynamic pH …

C Chu, Y Zang, J Li, Y Zou, W Gao, Y Lv, C Li, S Tong… - LWT, 2022 - Elsevier
A new strategy by coupling salting-out assisted liquid‒liquid extraction with dynamic pH
junction-sweeping-large volume sample stacking in capillary electrophoresis was proposed …

Recent Developments in the Detection of Organic Contaminants Using Molecularly Imprinted Polymers Combined with Various Analytical Techniques

T Nazim, A Lusina, M Cegłowski - Polymers, 2023 - mdpi.com
Molecularly imprinted polymers (MIPs) encompass a diverse array of polymeric matrices that
exhibit the unique capacity to selectively identify a designated template molecule through …

In-line sample concentration in capillary electrophoresis by cyclodextrin to admicelle microextraction

APJP Vaas, RB Yu, JP Quirino - Analytical and Bioanalytical Chemistry, 2022 - Springer
Cyclodextrins (CDs) as a pseudophase in pseudophase-to-pseudophase microextraction
(P2ME) in capillary zone electrophoresis (CZE) are proposed. In this P2ME mode called CD …

Rapid and simultaneous determination of free aromatic carboxylic acids and phenols in commercial juices by GC-MS after ethyl chloroformate derivatization

A Incocciati, E Di Fabio, A Boffi, A Bonamore… - Separations, 2021 - mdpi.com
Natural phenol and phenolic acids are widely distributed in the plant kingdom and the major
dietary sources include fruits and beverages derived therefrom. Over the past decades …

Determination of Tyrosine Kinase Inhibitors via Capillary Electrophoresis with Tandem Mass Spectrometry and Online Stacking Preconcentration

J Petr - Pharmaceuticals, 2023 - mdpi.com
Capillary electrophoresis connected with tandem mass spectrometry was employed for the
development of a method for determination of various tyrosine kinase inhibitors in plasma …