[HTML][HTML] Managing diabetes with nanomedicine: challenges and opportunities

O Veiseh, BC Tang, KA Whitehead… - Nature Reviews Drug …, 2015 - nature.com
Nanotechnology-based approaches hold substantial potential for improving the care of
patients with diabetes. Nanoparticles are being developed as imaging contrast agents to …

Nanomedicine-based strategies for diabetes: diagnostics, monitoring, and treatment

LR Lemmerman, D Das, N Higuita-Castro… - Trends in Endocrinology …, 2020 - cell.com
Traditional methods for diabetes management require constant and tedious glucose
monitoring (GM) and insulin injections, impacting quality of life. The global diabetic …

18F-radiolabeled analogs of exendin-4 for PET imaging of GLP-1 in insulinoma

DO Kiesewetter, H Gao, Y Ma, G Niu, Q Quan… - European journal of …, 2012 - Springer
Purpose Glucagon-like peptide type 1 (GLP-1) is an incretin peptide that augments glucose-
stimulated insulin release following oral consumption of nutrients. Its message is transmitted …

In vivo imaging of the glucagonlike peptide 1 receptor in the pancreas with 68Ga-labeled DO3A-exendin-4

RK Selvaraju, I Velikyan, L Johansson… - Journal of Nuclear …, 2013 - Soc Nuclear Med
The glucagonlike peptide 1 receptor (GLP-1R) is mainly expressed on β-cells in the islets of
Langerhans and is therefore an attractive target for imaging of the β-cell mass. In the present …

64Cu- and 68Ga-Labelled [Nle14,Lys40(Ahx-NODAGA)NH2]-Exendin-4 for Pancreatic Beta Cell Imaging in Rats

M Kirsi, Y Cheng-Bin, F Veronica, I Tamiko… - Molecular imaging and …, 2014 - Springer
Purpose Glucagon-like peptide-1 receptor (GLP-1R) is a molecular target for imaging of
pancreatic beta cells. We compared the ability of [Nle 14, Lys 40 (Ahx-NODAGA-64 Cu) NH …

Molecular imaging of β-cells: diabetes and beyond

W Wei, EB Ehlerding, X Lan, QY Luo, W Cai - Advanced drug delivery …, 2019 - Elsevier
Since diabetes is becoming a global epidemic, there is a great need to develop early β-cell
specific diagnostic techniques for this disorder. There are two types of diabetes (ie, type 1 …

Porphyrins and related macrocycles: Combining photosensitization with radio-or optical-imaging for next generation theranostic agents

J Sandland, N Malatesti, R Boyle - Photodiagnosis and photodynamic …, 2018 - Elsevier
This review summarises recent research into combining the photosensitizing properties of
porphyrins with imaging techniques such as PET and NIR fluorescence for so called …

[HTML][HTML] Diagnostic and prognostic utility of non-invasive imaging in diabetes management

C Barsanti, F Lenzarini, C Kusmic - World journal of diabetes, 2015 - ncbi.nlm.nih.gov
Medical imaging technologies are acquiring an increasing relevance to assist clinicians in
diagnosis and to guide management and therapeutic treatment of patients, thanks to their …

Glucose-dependent insulinotropic polypeptide receptors in most gastroenteropancreatic and bronchial neuroendocrine tumors

B Waser, R Rehmann, C Sanchez… - The Journal of …, 2012 - academic.oup.com
Context: Gastrointestinal peptide hormone receptors overexpressed in neuroendocrine
tumors (NET), such as somatostatin or glucagon-like peptide-1 (GLP-1) receptors, are used …

Targeting type 1 diabetes: selective approaches for new therapies

DF Sheehy, SP Quinnell, AJ Vegas - Biochemistry, 2019 - ACS Publications
The clinical onset of type 1 diabetes is characterized by the destruction of the insulin-
producing β cells of the pancreas and is caused by autoantigen-induced inflammation …