Drug discovery from natural sources is going through a renaissance, having spent many
decades in the shadow of synthetic molecule drug discovery, despite the fact that natural …

As an important part in international disease, mental disorders seriously damage human
health and social stability, which show the complex pathogenesis and increasing incidence …

Background Depression is the most known complication of type 2 diabetes mellitus (T2DM).
Aerobic exercise improves glycemic control in T2DM, although the underlying mechanisms …

Abstract Ethnopharmacological relevance Traditional Chinese medicine (TCM) has been
applied for more than 2000 years. However, modern basic research on the safety of TCMs is …

Abstract Ethnopharmacological relevance Although the Traditional Chinese Medicine (TCM)
prescription of Danggui Shaoyao San (DSS) presents substantial clinical efficacy and …

Epilepsy affects about 65 million people in the world, which makes this disease a public
health problem. In addition to the incidence of recurrent seizures, this neurological condition …

Anxiety is the most prevalent brain disorder and a common cause of human disability.
Animal models are critical for understanding anxiety pathogenesis and its pharmacotherapy …

The ability of the nervous system to detect a wide range of noxious stimuli is crucial to avoid
life-threatening injury and to trigger protective behavioral and physiological responses. Pain …

Salidroside, an active ingredient in Rhodiola rosea, has potent protective activity against
cerebral ischemia. However, the mechanisms underlying its pharmacological actions are …

Immunosenescence is the degeneration of immunological organs and cells due to aging.
Some plants and fungi may have anti-aging benefits through regulating …