Epigenetics and pulmonary diseases in the horizon of precision medicine: a review

G Benincasa, DL DeMeo, K Glass… - European …, 2021 - Eur Respiratory Soc
Epigenetic mechanisms represent potential molecular routes which could bridge the gap
between genetic background and environmental risk factors contributing to the …

Pathophysiology and genomics of bronchiectasis

L Perea, R Faner, JD Chalmers… - European Respiratory …, 2024 - err.ersjournals.com
Bronchiectasis is a complex and heterogeneous inflammatory chronic respiratory disease
with an unknown cause in around 30–40% of patients. The presence of airway infection …

Machine learning characterization of COPD subtypes: insights from the COPDGene study

PJ Castaldi, A Boueiz, J Yun, RSJ Estepar, JC Ross… - Chest, 2020 - Elsevier
COPD is a heterogeneous syndrome. Many COPD subtypes have been proposed, but there
is not yet consensus on how many COPD subtypes there are and how they should be …

Protein biomarkers for COPD outcomes

KA Serban, KA Pratte, RP Bowler - Chest, 2021 - Elsevier
COPD is a clinically heterogeneous syndrome characterized by injury to airways, airspaces,
and lung vasculature and usually caused by tobacco smoke and/or air pollution exposure …

[HTML][HTML] Integrative weighted molecular network construction from transcriptomics and genome wide association data to identify shared genetic biomarkers for COPD …

B Banaganapalli, B Mallah, KS Alghamdi… - Plos one, 2022 - journals.plos.org
Chronic obstructive pulmonary disease (COPD) is a multifactorial progressive airflow
obstruction in the lungs, accounting for high morbidity and mortality across the world. This …

Epigenetic regulation of inflammation: The metabolomics connection

S Rath, YM Hawsawi, F Alzahrani, MI Khan - Seminars in Cell & …, 2022 - Elsevier
Epigenetic factors are considered the regulator of complex machinery behind inflammatory
disorders and significantly contributed to the expression of inflammation-associated genes …

Prognostic biomarkers based on proteomic technology in COPD: a recent review

H Fang, Y Liu, Q Yang, S Han… - International Journal of …, 2023 - Taylor & Francis
Chronic obstructive pulmonary disease (COPD) is a common heterogeneous respiratory
disease which is characterized by persistent and incompletely reversible airflow limitation …

Predictive modeling for metabolomics data

T Ghosh, W Zhang, D Ghosh, K Kechris - Computational methods and …, 2020 - Springer
In recent years, mass spectrometry (MS)-based metabolomics has been extensively applied
to characterize biochemical mechanisms, and study physiological processes and …

The axis of the receptor for advanced glycation endproducts in asthma and allergic airway disease

TN Perkins, ML Donnell, TD Oury - Allergy, 2021 - Wiley Online Library
Asthma is a generalized term that describes a scope of distinct pathologic phenotypes of
variable severity, which share a common complication of reversible airflow obstruction …

[HTML][HTML] Seven ferroptosis-specific expressed genes are considered as potential biomarkers for the diagnosis and treatment of cigarette smoke-induced chronic …

Z Lin, Y Xu, L Guan, L Qin, J Ding… - Annals of translational …, 2022 - ncbi.nlm.nih.gov
Background Chronic obstructive pulmonary disease (COPD) is a chronic respiratory disease
characterized by incomplete reversible airway obstruction, with high mortality and disability …