Adjuvant physiochemistry and advanced nanotechnology for vaccine development
Vaccines comprising innovative adjuvants are rapidly reaching advanced translational
stages, such as the authorized nanotechnology adjuvants in mRNA vaccines against COVID …
stages, such as the authorized nanotechnology adjuvants in mRNA vaccines against COVID …
[HTML][HTML] Immune checkpoint inhibitors for vaccine improvements: current status and new approaches
In recent years, the use of immune checkpoint inhibitors (ICIs) in combination with approved
or experimental vaccines has proven to be a promising approach to improve vaccine …
or experimental vaccines has proven to be a promising approach to improve vaccine …
[HTML][HTML] Polypharmacological cell-penetrating peptides from venomous marine animals based on immunomodulating, antimicrobial, and anticancer properties
S Hemmati, H Rasekhi Kazerooni - Marine Drugs, 2022 - mdpi.com
Complex pathological diseases, such as cancer, infection, and Alzheimer's, need to be
targeted by multipronged curative. Various omics technologies, with a high rate of data …
targeted by multipronged curative. Various omics technologies, with a high rate of data …
Multidomain peptide hydrogel adjuvants elicit strong bias towards humoral immunity
Adjuvants play a critical role in enhancing vaccine efficacy; however, there is a need to
develop new immunomodulatory compounds to address emerging pathogens and to …
develop new immunomodulatory compounds to address emerging pathogens and to …
Dynamic imine bonding facilitates mannan release from a nanofibrous peptide hydrogel
Recently, there has been increased interest in using mannan as an immunomodulatory
bioconjugate. Despite notable immunological and functional differences between the …
bioconjugate. Despite notable immunological and functional differences between the …
[HTML][HTML] Adjuvants approved for human use: What do we know and what do we need to know for designing good adjuvants?
C Reyes, MA Patarroyo - European Journal of Pharmacology, 2023 - Elsevier
Adjuvants represent one of the most significant biotechnological solutions regarding vaccine
development, thereby broadening the amount of candidates which can now be used and …
development, thereby broadening the amount of candidates which can now be used and …
[HTML][HTML] A-910823, a squalene-based emulsion adjuvant, induces T follicular helper cells and humoral immune responses via α-tocopherol component
Y Yoshioka, K Kobiyama, T Hayashi, M Onishi… - Frontiers in …, 2023 - frontiersin.org
Background Adjuvants are chemical or biological materials that enhance the efficacy of
vaccines. A-910823 is a squalene-based emulsion adjuvant used for S-268019-b, a novel …
vaccines. A-910823 is a squalene-based emulsion adjuvant used for S-268019-b, a novel …
PRR-HyPred: A two-layer hybrid framework to predict pattern recognition receptors and their families by employing sequence encoded optimal features
Pattern recognition receptors (PRRs) recognize distinct features on the surface of pathogens
or damaged cells and play key roles in the innate immune system. PRRs are divided into …
or damaged cells and play key roles in the innate immune system. PRRs are divided into …
[HTML][HTML] Emerging Field-Effect Transistor Biosensors for Life Science Applications
A Panahi, E Ghafar-Zadeh - Bioengineering, 2023 - mdpi.com
Field-effect transistors (FETs) have gained significant interest and hold great potential as
groundbreaking sensing technology in the fields of biosensing and life science research …
groundbreaking sensing technology in the fields of biosensing and life science research …
[HTML][HTML] TLR9 and STING agonists cooperatively boost the immune response to SARS-CoV-2 RBD vaccine through an increased germinal center B cell response and …
JX Yang, JC Tseng, CF Tien, CY Lee… - … Journal of Biological …, 2023 - ncbi.nlm.nih.gov
Vaccines are a powerful medical intervention for preventing epidemic diseases. Efficient
inactivated or protein vaccines typically rely on an effective adjuvant to elicit an immune …
inactivated or protein vaccines typically rely on an effective adjuvant to elicit an immune …