Biomarkers in whichever modality are tremendously important in diagnosing of disease,
tracking disease progression and clinical trials. This applies in particular for disorders with a …

It is well known that most brain disorders are complex diseases, such as Alzheimer's
disease (AD) and schizophrenia (SCZ). In general, brain regions and their interactions can …

Abstract See Nieuwhof and Helmich (doi: 10.1093/brain/awx267) for a scientific commentary
on this article. Parkinson's disease is a neurodegenerative disorder characterized by …

The objective was to assess dynamic functional connectivity (FC) and local/global
connectivity in Parkinson's disease (PD) patients with mild cognitive impairment (PD-MCI) …

Dementia in Parkinson's disease affects 50% of patients within 10 years of diagnosis but
there is wide variation in severity and timing. Thus, robust neuroimaging prediction of …

Parkinson's disease (PD) is a progressive, chronic, and neurodegenerative disorder that is
primarily diagnosed by clinical examinations and magnetic resonance imaging (MRI). In this …

The hallmark pathology underlying Parkinson disease (PD) is progressive synucleinopathy,
beginning in caudal brainstem that later spreads rostrally. However, the primarily subcortical …

Dynamic functional connectivity (DFC) was established in the past decade as a potent
approach to reveal non-trivial, time-varying properties of neural interactions–such as their …

Background Functional brain connectivity alterations may be detectable even before the
occurrence of brain atrophy, indicating their potential as early markers of pathological …

Objective: Inferring causal or effective connectivity between measured timeseries is crucial
to understanding directed interactions in complex systems. This task is especially …