[HTML][HTML] Lipids and cancer: Emerging roles in pathogenesis, diagnosis and therapeutic intervention

LM Butler, Y Perone, J Dehairs, LE Lupien… - Advanced drug delivery …, 2020 - Elsevier
With the advent of effective tools to study lipids, including mass spectrometry-based
lipidomics, lipids are emerging as central players in cancer biology. Lipids function as …

[HTML][HTML] The mevalonate pathway, a metabolic target in cancer therapy

B Guerra, C Recio, H Aranda-Tavío… - Frontiers in …, 2021 - frontiersin.org
A hallmark of cancer cells includes a metabolic reprograming that provides energy, the
essential building blocks, and signaling required to maintain survival, rapid growth …

[HTML][HTML] The potential use of simvastatin for cancer treatment: A review

JA Duarte, ALB de Barros, EA Leite - Biomedicine & Pharmacotherapy, 2021 - Elsevier
Statins, typically used to reduce lipid levels, have been rediscovered for exhibiting
anticancer activities. Among them, especially simvastatin may influence the proliferation …

[HTML][HTML] Согласованное мнение российских экспертов по профилактике, диагностике и лечению сердечно-сосудистой токсичности противоопухолевой …

ЮА Васюк, ГЕ Гендлин, ЕИ Емелина… - Российский …, 2021 - cyberleninka.ru
АВ—атриовентрикулярный (ая) АГ—артериальная гипертензия АД—артериальное
давление АТ—артериальный тромбоз АТО—атеротромботические осложнения АТФ …

LDL, HDL and endocrine-related cancer: From pathogenic mechanisms to therapies

G Revilla, L Cedó, M Tondo, A Moral, JI Pérez… - Seminars in Cancer …, 2021 - Elsevier
Cholesterol is essential for a variety of functions in endocrine-related cells, including
hormone and steroid production. We have reviewed the progress to date in research on the …

The evolving landscape of PCSK9 inhibition in cancer

PP Oza, K Kashfi - European Journal of Pharmacology, 2023 - Elsevier
Cancer is a disease with a significant global burden in terms of premature mortality, loss of
productivity, healthcare expenditures, and impact on mental health. Recent decades have …

Statin-induced myopathy: translational studies from preclinical to clinical evidence

GM Camerino, N Tarantino, I Canfora… - International journal of …, 2021 - mdpi.com
Statins are the most prescribed and effective drugs to treat cardiovascular diseases (CVD).
Nevertheless, these drugs can be responsible for skeletal muscle toxicity which leads to …

Statin Use, Cholesterol Level, and Mortality Among Females With Breast Cancer

MO Murto, N Simolin, O Arponen, A Siltari… - JAMA Network …, 2023 - jamanetwork.com
Importance Several studies have reported an association between the use of statins and
breast cancer (BC) mortality. However, most of these studies did not take into account the …

Is cholesterol a risk factor for breast cancer incidence and outcome?

CB Hassen, C Goupille, C Vigor, T Durand… - The Journal of Steroid …, 2023 - Elsevier
Cholesterol plays important roles in many physiological processes, including cell membrane
structure and function, hormone synthesis, and the regulation of cellular homeostasis. The …

Gut microbiome: A possible common therapeutic target for treatment of atherosclerosis and cancer

WK Wu, EA Ivanova, AN Orekhov - Seminars in Cancer Biology, 2021 - Elsevier
Human gut microbiota is a dynamic and variable system that can change over time and in
response to different diets and treatments. There is currently no doubt that gut microbiota …