Inclusion and diversity in clinical trials: actionable steps to drive lasting change
MD Kelsey, B Patrick-Lake, R Abdulai… - Contemporary Clinical …, 2022 - Elsevier
Background Improving diversity in clinical trials is essential in order to produce
generalizable results. Although the importance of representation has become increasingly …
generalizable results. Although the importance of representation has become increasingly …
Trials using deferred consent in the emergency setting: a systematic review and narrative synthesis of stakeholders' attitudes
A Fitzpatrick, F Wood, V Shepherd - Trials, 2022 - Springer
Background Patients with acute conditions often lack the capacity to provide informed
consent, and narrow therapeutic windows mean there is no time to seek consent from …
consent, and narrow therapeutic windows mean there is no time to seek consent from …
Unpacking the 'black box of horrendousness': a qualitative exploration of the barriers and facilitators to conducting trials involving adults lacking capacity to consent
V Shepherd, K Hood, F Wood - Trials, 2022 - Springer
Background Trials involving adults who lack capacity to consent encounter a range of ethical
and methodological challenges, resulting in these populations frequently being excluded …
and methodological challenges, resulting in these populations frequently being excluded …
Ethical considerations in clinical trials for disorders of consciousness
As the clinical trial landscape for patients with disorders of consciousness (DoC) expands,
consideration of associated ethical challenges and opportunities is of ever-increasing …
consideration of associated ethical challenges and opportunities is of ever-increasing …
Fairdiff: Fair segmentation with point-image diffusion
Fairness is an important topic for medical image analysis, driven by the challenge of
unbalanced training data among diverse target groups and the societal demand for …
unbalanced training data among diverse target groups and the societal demand for …
Complex and alternate consent pathways in clinical trials: methodological and ethical challenges encountered by underserved groups and a call to action
Background Informed consent is considered a fundamental requirement for participation in
trials, yet obtaining consent is challenging in a number of populations and settings. This may …
trials, yet obtaining consent is challenging in a number of populations and settings. This may …
A call to action for more disability-inclusive health policy and systems research
To date, the exclusion of people with disability participating in research has limited the
evidence base informing health system strengthening policy and practice more generally …
evidence base informing health system strengthening policy and practice more generally …
Barriers and facilitators to the recruitment of disabled people to clinical trials: a scoping review
S Shariq, AM Cardoso Pinto, SS Budhathoki, M Miller… - Trials, 2023 - Springer
Introduction Underrepresentation of disabled groups in clinical trials results in an
inadequate evidence base for their clinical care, which drives health inequalities. This study …
inadequate evidence base for their clinical care, which drives health inequalities. This study …
Increasing diversity of patients in radiation oncology clinical trials
Radiation oncology clinical trials lack full representation of the ethnic and racial diversity
present in the general United States and in the cancer patient population. There are low …
present in the general United States and in the cancer patient population. There are low …
Unethical governance: capacity legislation and the exclusion of people diagnosed with dementias from research
JR Fletcher - Research Ethics, 2021 - journals.sagepub.com
This paper considers the potential for the Mental Capacity Act (MCA) of England and Wales
to incentivise the exclusion of people with dementia from research. The MCA is intended to …
to incentivise the exclusion of people with dementia from research. The MCA is intended to …