[HTML][HTML] The implications of exosomes in pregnancy: emerging as new diagnostic markers and therapeutics targets
Extracellular vehicles (EVs) are a heterogeneous group of cell and membranous particles
originating from different cell compartments. EVs participate in many essential physiological …
originating from different cell compartments. EVs participate in many essential physiological …
The cellular dynamics of neural tube formation
M van der Spuy, JX Wang… - Biochemical Society …, 2023 - portlandpress.com
The vertebrate brain and spinal cord arise from a common precursor, the neural tube, which
forms very early during embryonic development. To shape the forming neural tube, changes …
forms very early during embryonic development. To shape the forming neural tube, changes …
Systems biology analysis of human genomes points to key pathways conferring spina bifida risk
V Aguiar-Pulido, P Wolujewicz… - Proceedings of the …, 2021 - National Acad Sciences
Spina bifida (SB) is a debilitating birth defect caused by multiple gene and environment
interactions. Though SB shows non-Mendelian inheritance, genetic factors contribute to an …
interactions. Though SB shows non-Mendelian inheritance, genetic factors contribute to an …
[HTML][HTML] A quest for genetic causes underlying signaling pathways associated with neural tube defects
S Rai, L Leydier, S Sharma, J Katwala… - Frontiers in Pediatrics, 2023 - frontiersin.org
Neural tube defects are dreadful congenital deformities of the nervous system that occur
owing to failure of normal neural tube closure. Genetic and non-genetic factors contribute to …
owing to failure of normal neural tube closure. Genetic and non-genetic factors contribute to …
Cigarette smoke induced neural tube defects by down‐regulating noggin expression
C Yin, H Cai, D Yang, Y Jian, J Zhang… - Birth Defects …, 2021 - Wiley Online Library
Background Maternal smoking or passive smoking during gestation increases the risk of
congenital birth defects, including neural tube defects (NTDs). Cigarette smoke is a …
congenital birth defects, including neural tube defects (NTDs). Cigarette smoke is a …
[HTML][HTML] Somatic and de novo Germline Variants of MEDs in Human Neural Tube Defects
T Tian, X Cao, Y Chen, L Jin, Z Li, X Han… - Frontiers in cell and …, 2021 - frontiersin.org
Background Neural tube defects (NTDs) are among the most common and severe
congenital defects in humans. Their genetic etiology is complex and remains poorly …
congenital defects in humans. Their genetic etiology is complex and remains poorly …
Neural tube defects and associated factors among neonates admitted to the neonatal intensive care units in Hiwot Fana specialized University hospital, Harar …
Y Edris, H Abdurahman, A Desalew… - Global Pediatric …, 2020 - journals.sagepub.com
Background: Neural tube defects are a major public health problem and substantially
contribute to morbidity and mortality, particularly in low-income countries, including Ethiopia …
contribute to morbidity and mortality, particularly in low-income countries, including Ethiopia …
Genome‐wide analysis of spina bifida risk variants in a case–control study from Bangladesh
G Tindula, B Issac, SK Mukherjee… - Birth Defects …, 2024 - Wiley Online Library
Background Human studies of genetic risk factors for neural tube defects, severe birth
defects associated with long‐term health consequences in surviving children, have …
defects associated with long‐term health consequences in surviving children, have …
[HTML][HTML] Identification and functional analysis of rare HECTD1 missense variants in human neural tube defects
Neural tube defects (NTDs) are severe malformations of the central nervous system that
arise from failure of neural tube closure. HECTD1 is an E3 ubiquitin ligase required for …
arise from failure of neural tube closure. HECTD1 is an E3 ubiquitin ligase required for …
Identification of common candidate genes and pathways for Spina Bifida and Wilm's Tumor using an integrative bioinformatics analysis
Abstract Spina Bifida (SB) and Wilm's Tumor (WT) are conditions, both associated with
children. Several studies have shown that WT later develops in SB patients, which led us to …
children. Several studies have shown that WT later develops in SB patients, which led us to …