In the human eye, a transparent cornea and lens combine to form the" refracton" to focus
images on the retina. This requires the refracton to have a high refractive index" n," mediated …

Worldwide 20,000–40,000 children with congenital or childhood cataract are born every
year with varying degrees and patterns of lens opacification with a broad aetiology. In most …

High levels of reactive oxygen species such as hydrogen peroxide (H 2 O 2) cause oxidative
stress in the lens and lead to cataractogenesis. The present investigation was undertaken to …

Aquaporins (AQPs) are a highly conserved group of membrane proteins that play critical
roles in water and small solute transport across epithelial and endothelial barriers. The aim …

Epithelial cells and differentiated fiber cells represent distinct compartments in the ocular
lens. While previous studies have revealed proteins that are preferentially expressed in …

The lens is an avascular organ that is supported by an internal circulation of water and
solutes. This circulation is driven by ion pumps, channels and transporters in epithelial cells …

Lens, an avascular tissue involved in light transmission, generates an internal
microcirculatory system to promote ion and fluid circulation, thus providing nutrients to …

The avascular eye lens generates its own microcirculation that is required for maintaining
lifelong lens transparency. The microcirculation relies on sodium ion flux, an extensive …

Breast cancer (BC) relapse, despite clinical advancement, remains one of the biggest issues
in the field. Intercellular communication, specifically via connexin (Cx)-mediated gap …

Aquaporins (AQPs), ordinarily regarded as water channels, have recently been shown to
participate in other cellular functions such as cell-to-cell adhesion, cell migration, cell …