Modern views of machine learning for precision psychiatry

ZS Chen, IR Galatzer-Levy, B Bigio, C Nasca, Y Zhang - Patterns, 2022 - cell.com
In light of the National Institute of Mental Health (NIMH)'s Research Domain Criteria (RDoC),
the advent of functional neuroimaging, novel technologies and methods provide new …

The synergy between deep learning and organs-on-chips for high-throughput drug screening: a review

M Dai, G Xiao, M Shao, YS Zhang - Biosensors, 2023 - mdpi.com
Organs-on-chips (OoCs) are miniature microfluidic systems that have arguably become a
class of advanced in vitro models. Deep learning, as an emerging topic in machine learning …

Off-policy evaluation for human feedback

Q Gao, G Gao, J Dong, V Tarokh… - Advances in Neural …, 2023 - proceedings.neurips.cc
Off-policy evaluation (OPE) is important for closing the gap between offline training and
evaluation of reinforcement learning (RL), by estimating performance and/or rank of target …

Offline learning of closed-loop deep brain stimulation controllers for parkinson disease treatment

Q Gao, SL Schmidt, A Chowdhury, G Feng… - Proceedings of the …, 2023 - dl.acm.org
Deep brain stimulation (DBS) has shown great promise toward treating motor symptoms
caused by Parkinson's disease (PD), by delivering electrical pulses to the Basal Ganglia …

Decision support for personalized therapy in implantable medical devices: A digital twin approach

H Yang, Z Jiang - Expert Systems with Applications, 2024 - Elsevier
Abstract Implantable Medical Devices (IMDs) offer timely therapeutic interventions for life-
threatening conditions without disrupting patients' daily activities. Given the substantial …

Adaptive parameter modulation of deep brain stimulation based on improved supervisory algorithm

Y Zhu, J Wang, H Li, C Liu, WM Grill - Frontiers in neuroscience, 2021 - frontiersin.org
Clinically deployed deep brain stimulation (DBS) for the treatment of Parkinson's disease
operates in an open loop with fixed stimulation parameters, and this may result in high …

Offline policy evaluation for learning-based deep brain stimulation controllers

Q Gao, SL Schmidt, K Kamaravelu… - 2022 ACM/IEEE 13th …, 2022 - ieeexplore.ieee.org
Deep brain stimulation (DBS) is an effective procedure to treat motor symptoms caused by
nervous system disorders such as Parkinson's disease (PD). Although existing implantable …

{\epsilon}-Neural Thompson Sampling of Deep Brain Stimulation for Parkinson Disease Treatment

HL Hsu, Q Gao, M Pajic - arXiv preprint arXiv:2403.06814, 2024 - arxiv.org
Deep Brain Stimulation (DBS) stands as an effective intervention for alleviating the motor
symptoms of Parkinson's disease (PD). Traditional commercial DBS devices are only able to …

BGRL: Basal Ganglia inspired Reinforcement Learning based framework for deep brain stimulators

H Agarwal, H Rathore - Artificial Intelligence in Medicine, 2024 - Elsevier
Abstract Deep Brain Stimulation (DBS) is an implantable medical device used for electrical
stimulation to treat neurological disorders. Traditional DBS devices provide fixed frequency …

Robust exploration with adversary via Langevin Monte Carlo

HL Hsu, M Pajic - 6th Annual Learning for Dynamics & …, 2024 - proceedings.mlr.press
In the realm of Deep Q-Networks (DQNs), numerous exploration strategies have
demonstrated efficacy within controlled environments. However, these methods encounter …