Genetic risk can be decreased: quitting smoking decreases and delays lung cancer for smokers with high and low CHRNA5 risk genotypes—a meta-analysis
Background Recent meta-analyses show that individuals with high risk variants in CHRNA5
on chromosome 15q25 are likely to develop lung cancer earlier than those with low-risk …
on chromosome 15q25 are likely to develop lung cancer earlier than those with low-risk …
Telomere-associated genes and telomeric lncRNAs are biomarker candidates in lung squamous cell carcinoma (LUSC)
CB Storti, RA de Oliveira, M de Carvalho… - … and molecular pathology, 2020 - Elsevier
In the past decade, research efforts were made to identify molecular biomarkers useful as
therapeutic targets in Non-Small Cell Lung Cancer (NSCLC), the most frequent type of lung …
therapeutic targets in Non-Small Cell Lung Cancer (NSCLC), the most frequent type of lung …
Lack of Associations of CHRNA5-A3-B4 Genetic Variants with Smoking Cessation Treatment Outcomes in Caucasian Smokers despite Associations with Baseline …
CHRNA5-A3-B4 variants, rs16969968, rs588765 and rs578776, are consistently associated
with tobacco consumption among smokers, but the association with smoking cessation is …
with tobacco consumption among smokers, but the association with smoking cessation is …
DNA repair as an emerging target for COPD-lung cancer overlap
CR Sears - Respiratory investigation, 2019 - Elsevier
Cigarette smoking is the leading cause of lung cancer and chronic obstructive pulmonary
disease (COPD). Many of the detrimental effects of cigarette smoke have been attributed to …
disease (COPD). Many of the detrimental effects of cigarette smoke have been attributed to …
Genetic modifiers of radon-induced lung cancer risk: a genome-wide interaction study in former uranium miners
A Rosenberger, RJ Hung, DC Christiani… - International archives of …, 2018 - Springer
Purpose Radon is a risk factor for lung cancer and uranium miners are more exposed than
the general population. A genome-wide interaction analysis was carried out to identify …
the general population. A genome-wide interaction analysis was carried out to identify …
miRNA regulated pathways in late stage murine lung development
S Mujahid, T Logvinenko, MAV Volpe… - BMC developmental …, 2013 - Springer
Background MicroRNAs play important roles in regulating biological processes, including
organ morphogenesis and maturation. However, little is known about specific pathways …
organ morphogenesis and maturation. However, little is known about specific pathways …
Genetic determinants of cytochrome P450 2A6 activity and biomarkers of tobacco smoke exposure in relation to risk of lung cancer development in the S hanghai …
Cytochrome P450 2A6 (CYP2A6) catalyzes nicotine metabolism and contributes to the
metabolism of the tobacco‐specific lung carcinogen, NNK. Genetic variation in CYP2A6 may …
metabolism of the tobacco‐specific lung carcinogen, NNK. Genetic variation in CYP2A6 may …
The association between dietary vitamin B12 and lung cancer risk: findings from a prospective cohort study
Background Since previous epidemiological studies reported inconsistent associations
between dietary vitamin B 12 intake and lung cancer risk, more studies are warranted to …
between dietary vitamin B 12 intake and lung cancer risk, more studies are warranted to …
LncRNA MAGI2-AS3 is downregulated in non-small cell lung cancer and may be a sponge of miR-25
Y Sui, W Chi, L Feng, J Jiang - BMC pulmonary medicine, 2020 - Springer
Background This study aimed to investigate the role of lncRNA MAGI2-AS3 in non-small cell
lung cancer (NSCLC). Methods Expression levels of MAGI2-AS3 and RECK mRNA in two …
lung cancer (NSCLC). Methods Expression levels of MAGI2-AS3 and RECK mRNA in two …
[HTML][HTML] Positron emission tomography-computed tomography in the management of lung cancer: An update
P Sharma, H Singh, S Basu… - South Asian journal of …, 2013 - ncbi.nlm.nih.gov
This communication presents an update on the current role of positron emission tomography-
computed tomography (PET-CT) in the various clinical decision-making steps in lung …
computed tomography (PET-CT) in the various clinical decision-making steps in lung …