There has been much interest recently in the structure of small peptides in solution. A recent
study by Bradley and co‐workers [(1989) in Techniques of Protein Chemistry, Hugli, TE, Ed …

A simple physical model is developed to study some characteristics of DNA dynamics. The
model uses only a few degrees of freedom so that DNA dynamics can be simulated over …

Detailed studies of structures of biological macromolecules, even in simplified models,
involve many costly and time‐consuming calculations. Any thorough methods require …

Yatakemycin (YTM) is an extraordinarily toxic DNA alkylating agent with potent antimicrobial
and antitumor properties and is the most recent addition to the CC-1065 and duocarmycin …

DNA repair enzymes induce base flipping in the process of damage recognition.
Endonuclease V initiates the repair of cis, syn thymine dimers (TD) produced in DNA by UV …

Damaged or mismatched DNA bases result in the formation of physical defects in double-
stranded DNA. In vivo, defects in DNA must be rapidly and efficiently repaired to maintain …

The eukaryotic genome contains chromosomal loci with a high transcription-promoting
potential. For their identification in cultured cells, transfer of a reporter gene has to be …

β-Cyclodextrin, which forms stable host− guest complexes with purine bases, induces the
melting of RNA and DNA duplexes below their normal melting temperatures. α-Cyclodextrin …

In a previous experimental study, we proposed that the bending and torsional stiffness of
DNA display a systematic sequence dependence. Subsequently, we developed an elastic …

In an effort to develop a dielectric screening function for molecular dynamics simulations of
biomolecules in implicit solvent, effective dielectric constants (Deff) for a large number of …