Pathophysiology of progressive nephropathies

G Remuzzi, T Bertani - New England Journal of Medicine, 1998 - Mass Medical Soc
In patients with renal diseases characterized by proteinuria, the initial insult to the kidney is
usually followed by a progressive decline in the glomerular filtration rate. This decline has …

Understanding the nature of renal disease progression

G Remuzzi, P Ruggenenti, A Benigni - Kidney international, 1997 - Elsevier
Among the several theories on the pathophysiology of progressive nephropathies [1—41,
the most convincing one [1, 2] suggests that the initial reduction in nephron number …

[HTML][HTML] Urinary protein excretion rate is the best independent predictor of ESRF in non-diabetic proteinuric chronic nephropathies

P Ruggenenti, A Perna, L Mosconi, R Pisoni… - Kidney international, 1998 - Elsevier
Urinary protein excretion rate is the best independent predictor of ESRF in non-diabetic
proteinuric chronic nephropathies. We investigated the predictors of the rate of glomerular …

Sympathetic hyperactivity in chronic renal failure: a wake-up call

HA Koomans, PJ Blankestijn… - Journal of the American …, 2004 - journals.lww.com
Sympathetic hyperactivity plays an important and distinct role in hypertension associated
with chronic renal failure (CRF). Renal ischemia, elevated angiotensin II, and suppressed …

Causes and consequences of increased sympathetic activity in renal disease

JA Joles, HA Koomans - Hypertension, 2004 - Am Heart Assoc
Much evidence indicates increased sympathetic nervous activity (SNA) in renal disease.
Renal ischemia is probably a primary event leading to increased SNA. Increased SNA often …

Effect of low-dose perindopril/indapamide on albuminuria in diabetes: preterax in albuminuria regression: PREMIER

CE Mogensen, G Viberti, S Halimi, E Ritz, L Ruilope… - …, 2003 - Am Heart Assoc
Microalbuminuria in diabetes is a risk factor for early death and an indicator for aggressive
blood pressure (BP) lowering. We compared a combination of 2 mg perindopril/0.625 mg …

[图书][B] Aboriginal primary health care: an evidence-based approach

S Couzos, R Murray - 2008 - eprints.jcu.edu.au
[Extract] Aboriginal Primary Health Care, 3rd edition is Australia's definitive guide to best-
practice management of the major health problems facing Aboriginal peoples and Torres …

Effect of ACE inhibitors in diabetic and nondiabetic chronic renal disease: a systematic overview of randomized placebo-controlled trials

AV Kshirsagar, MS Joy, SL Hogan, RJ Falk… - American journal of …, 2000 - Elsevier
Clinical trials have shown the beneficial effects of angiotensin-converting enzyme (ACE)
inhibitors in delaying the progression of diabetic renal disease. There is less evidence from …

[HTML][HTML] Mesenchymal stem cell-based treatment for microvascular and secondary complications of diabetes mellitus

GC Davey, SB Patil, A O'Loughlin… - Frontiers in …, 2014 - frontiersin.org
The worldwide increase in the prevalence of Diabetes mellitus (DM) has highlighted the
need for increased research efforts into treatment options for both the disease itself and its …

Double‐blind, randomised study of the effect of combined treatment with vitamin C and E on albuminuria in Type 2 diabetic patients

P Gaede, HE Poulsen, HH Parving… - Diabetic …, 2001 - Wiley Online Library
Aims Elevated levels of urinary albumin excretion rate (AER) predict high risk for
progressing to end‐stage renal disease. In streptozotocin‐induced diabetes …