The different types of striatal neuron show a range of vulnerabilities to a variety of insults.
This can be clearly seen in Huntington's disease where a well mapped pattern of …

Anterior ischemic optic neuropathy (AION) can be divided into nonarteritic (NAION) and
arteritic (AAION) forms. NAION makes up∼ 85% of all cases of AION, and until recently was …

We have identified a novel dominant mouse mutant that is characterised by fused toes on
the fore limbs and a thymic hyperplasia, in heterozygous animals. Homozygosity of the …

The study of risk factors and protective influences can yield clues to the pathogenesis of
Alzheimer's disease (AD). Intervention on such factors can effect disease prevention or …

Structure–function analysis as well as studies with knock-out and transgenic mice have
assigned distinct functions to c-Fos and Fra-1, two components of the transcription factor AP …

The p53 tumor-suppressor gene encodes a growth-regulatory protein that has been
implicated in programmed cell death. To investigate the possible role of p53 in neuronal …

HEAT SHOCK proteins (HSP) represent one of the most conserved groups of proteins
throughout evolution [reviewed in Refs 1 and 21. They have been found in all organisms …

Unexpected nerve cell death has been reported in several experimental situations where
neurons have been forced to re-enter the cell cycle after leaving the ventricular zone and …

Excitotoxicity is a process in which glutamate or other excitatory amino acids induce
neuronal cell death. Accumulating evidence suggests that excitotoxicity may contribute to …

The acute effect of global system for mobile communication (GSM) microwave exposure on
the genomic response of the central nervous system was studied in rats by measuring …